Purine salvage rescue by xanthine-guanine phosphoribosyltransferase (XGPRT) potentiates methotrexate resistance conferred by transfer of a mutated dihydrofolate reductase gene.

Purine salvage rescue by xanthine-guanine phosphoribosyltransferase (XGPRT) potentiates methotrexate resistance conferred by transfer of a mutated dihydrofolate reductase gene. Cancer Gene Ther. 1998 May-Jun; 5(3):144-9.

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subject areas

3T3 Cells
Animals
Antimetabolites, Antineoplastic
Base Sequence
Blotting, Northern
Bone Marrow Cells
DNA Primers
Drug Resistance, Neoplasm
Gene Transfer Techniques
Genetic Vectors
Male
Methotrexate
Mice
Mice, Inbred C57BL
Pentosyltransferases
Purines
Retroviridae
Tetrahydrofolate Dehydrogenase
Thioguanine

authors with profiles

Naoko Takebe