"Poloxamer" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nonionic polyoxyethylene-polyoxypropylene block co-polymer with the general formula HO(C2H4O)a(-C3H6O)b(C2H4O)aH. It is available in different grades which vary from liquids to solids. It is used as an emulsifying agent, solubilizing agent, surfactant, and wetting agent for antibiotics. Poloxamer is also used in ointment and suppository bases and as a tablet binder or coater. (Martindale The Extra Pharmacopoeia, 31st ed)
Below are MeSH descriptors whose meaning is more general than "Poloxamer".
Below are MeSH descriptors whose meaning is more specific than "Poloxamer".
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Below are the most recent publications written about "Poloxamer" by people in Profiles.
Carboxymethyl Cellulose, Pluronic, and Pullulan-Based Compositions Efficiently Enhance Antiadhesion and Tissue Regeneration Properties without Using Any Drug Molecules. ACS Appl Mater Interfaces. 2021 Apr 14; 13(14):15992-16006.
Pluronic block copolymers enhance the anti-myeloma activity of proteasome inhibitors. J Control Release. 2019 07 28; 306:149-164.
Chitosan coated PluronicF127 micelles for effective delivery of Amphotericin B in experimental visceral leishmaniasis. Int J Biol Macromol. 2017 Dec; 105(Pt 1):1220-1231.
Pluronic F-127 Stabilised Docetaxel Nanocrystals Improve Apoptosis by Mitochondrial Depolarization in Breast Cancer Cells: Pharmacokinetics and Toxicity Assessment. J Biomed Nanotechnol. 2015 Oct; 11(10):1747-63.
Nanoparticle-Based Topical Ophthalmic Gel Formulation for Sustained Release of Hydrocortisone Butyrate. AAPS PharmSciTech. 2016 Apr; 17(2):294-306.