"Helix-Loop-Helix Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recurring supersecondary structures characterized by 20 amino acids folding into two alpha helices connected by a non-helical "loop" segment. They are found in many sequence-specific DNA-BINDING PROTEINS and in CALCIUM-BINDING PROTEINS.
| Descriptor ID |
D018257
|
| MeSH Number(s) |
G02.111.570.820.709.275.500.360
|
| Concept/Terms |
Helix-Loop-Helix Motifs- Helix-Loop-Helix Motifs
- Helix Loop Helix Motifs
- Motif, Helix-Loop-Helix
- Helix-Loop-Helix Domains
- Helix Loop Helix Domains
- Helix-Loop-Helix Motif
- Helix Loop Helix Motif
- Helix-Loop-Helix Domain
- Helix Loop Helix Domain
- HLH Motifs
- HLH Motif
- Motif, HLH
- Motifs, HLH
- Motifs, Helix-Loop-Helix
- Motifs, Helix Loop Helix
|
Below are MeSH descriptors whose meaning is more general than "Helix-Loop-Helix Motifs".
Below are MeSH descriptors whose meaning is more specific than "Helix-Loop-Helix Motifs".
This graph shows the total number of publications written about "Helix-Loop-Helix Motifs" by people in this website by year, and whether "Helix-Loop-Helix Motifs" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Helix-Loop-Helix Motifs" by people in Profiles.
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Zhu G, Zhai P, He X, Wakeham N, Rodgers K, Li G, Tang J, Zhang XC. Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5. EMBO J. 2004 Oct 13; 23(20):3909-17.
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Zhai P, He X, Liu J, Wakeham N, Zhu G, Li G, Tang J, Zhang XC. The interaction of the human GGA1 GAT domain with rabaptin-5 is mediated by residues on its three-helix bundle. Biochemistry. 2003 Dec 02; 42(47):13901-8.
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Hewes RS, Park D, Gauthier SA, Schaefer AM, Taghert PH. The bHLH protein Dimmed controls neuroendocrine cell differentiation in Drosophila. Development. 2003 May; 130(9):1771-81.
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Bain G, Cravatt CB, Loomans C, Alberola-Ila J, Hedrick SM, Murre C. Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade. Nat Immunol. 2001 Feb; 2(2):165-71.