"Pro-Opiomelanocortin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 30-kDa protein synthesized primarily in the ANTERIOR PITUITARY GLAND and the HYPOTHALAMUS. It is also found in the skin and other peripheral tissues. Depending on species and tissues, POMC is cleaved by PROHORMONE CONVERTASES yielding various active peptides including ACTH; BETA-LIPOTROPIN; ENDORPHINS; MELANOCYTE-STIMULATING HORMONES; and others (GAMMA-LPH; CORTICOTROPIN-LIKE INTERMEDIATE LOBE PEPTIDE; N-terminal peptide of POMC or NPP).
- Pro Opiomelanocortin
- ACTH-Endorphin Precursor
- ACTH Endorphin Precursor
- Endorphin-ACTH Precursor
- Endorphin ACTH Precursor
- Corticotropin-beta-Lipotropin Precursor
- Corticotropin beta Lipotropin Precursor
- Pro Opiocortin
- Pro Opio Melanocortin
- ACTH-beta-Lipotropin Precursor
- ACTH beta Lipotropin Precursor
- Pro ACTH Endorphin
Below are MeSH descriptors whose meaning is more general than "Pro-Opiomelanocortin".
Below are MeSH descriptors whose meaning is more specific than "Pro-Opiomelanocortin".
This graph shows the total number of publications written about "Pro-Opiomelanocortin" by people in this website by year, and whether "Pro-Opiomelanocortin" was a major or minor topic of these publications.
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Below are the most recent publications written about "Pro-Opiomelanocortin" by people in Profiles.
17a-estradiol acts through hypothalamic pro-opiomelanocortin expressing neurons to reduce feeding behavior. Aging Cell. 2018 02; 17(1).
Up-regulation of the fetal baboon hypothalamo-pituitary-adrenal axis in intrauterine growth restriction: coincidence with hypothalamic glucocorticoid receptor insensitivity and leptin receptor down-regulation. Endocrinology. 2013 Jul; 154(7):2365-73.
Proopiomelanocortin peptides are not essential for development of ethanol-induced behavioral sensitization. Alcohol Clin Exp Res. 2009 Jul; 33(7):1202-7.
Failure of adrenal corticosterone production in POMC-deficient mice results from lack of integrated effects of POMC peptides on multiple factors. Am J Physiol Endocrinol Metab. 2008 Aug; 295(2):E446-55.
Development, maintenance, and function of the adrenal gland in early postnatal proopiomelanocortin-null mutant mice. Endocrinology. 2005 Jun; 146(6):2555-62.
Proopiomelanocortin processing in the anterior pituitary of the ovine fetus after lesion of the hypothalamic paraventricular nucleus. Endocrinology. 2005 Jun; 146(6):2665-73.
Long-term hypoxia enhances proopiomelanocortin processing in the near-term ovine fetus. Am J Physiol Regul Integr Comp Physiol. 2005 May; 288(5):R1178-84.
Activation of the sympathetic nervous system by galanin-like peptide--a possible link between leptin and metabolism. Endocrinology. 2003 Nov; 144(11):4709-17.
Regulation of proopiomelanocortin messenger ribonucleic acid levels in the ovine fetal anterior pituitary in vitro. Mol Cell Endocrinol. 2000 Dec 22; 170(1-2):175-84.
Corticotropin-releasing factor receptor expression in the pituitary of fetal sheep after lesion of the hypothalamic paraventricular nucleus. Endocrinology. 1999 Sep; 140(9):4292-9.