"Receptor, TIE-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A TIE receptor tyrosine kinase that is found almost exclusively on ENDOTHELIAL CELLS. It is required for both normal embryonic vascular development (NEOVASCULARIZATION, PHYSIOLOGIC) and tumor angiogenesis (NEOVASCULARIZATION, PATHOLOGIC).
- Receptor, TIE-2
- Receptor, TIE 2
- TIE-2 Receptor
- TIE2 Tyrosine Kinase
- Tyrosine Kinase, TIE2
- TIE-2 Receptor Tyrosine Kinase
- TIE 2 Receptor Tyrosine Kinase
- Tek Receptor
- Receptor, Tek
- Tie2 Receptor
- Receptor, Tie2
- Angiopoietin Receptor Tie-2
- Angiopoietin Receptor Tie 2
- Receptor Tie-2, Angiopoietin
- Tie-2, Angiopoietin Receptor
Below are MeSH descriptors whose meaning is more general than "Receptor, TIE-2".
Below are MeSH descriptors whose meaning is more specific than "Receptor, TIE-2".
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Below are the most recent publications written about "Receptor, TIE-2" by people in Profiles.
Heightened activation of embryonic megakaryocytes causes aneurysms in the developing brain of mice lacking podoplanin. Blood. 2021 05 20; 137(20):2756-2769.
Angiopoietin-1 is required for Schlemm's canal development in mice and humans. J Clin Invest. 2017 12 01; 127(12):4421-4436.
Angiopoietin receptor TEK mutations underlie primary congenital glaucoma with variable expressivity. J Clin Invest. 2016 07 01; 126(7):2575-87.
Radiation attenuates physiological angiogenesis by differential expression of VEGF, Ang-1, tie-2 and Ang-2 in rat brain. Radiat Res. 2011 Dec; 176(6):753-60.
A PEDF-derived peptide inhibits retinal neovascularization and blocks mobilization of bone marrow-derived endothelial progenitor cells. Exp Diabetes Res. 2012; 2012:518426.
The chromatin-remodeling enzyme BRG1 plays an essential role in primitive erythropoiesis and vascular development. Development. 2008 Feb; 135(3):493-500.
Bone marrow dysfunction in mice lacking the cytokine receptor gp130 in endothelial cells. Blood. 2005 Dec 15; 106(13):4093-101.