Ubiquitin-Conjugating Enzymes
"Ubiquitin-Conjugating Enzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that form a thioester bond to UBIQUITIN with the assistance of UBIQUITIN-ACTIVATING ENZYMES. They transfer ubiquitin to the LYSINE of a substrate protein with the assistance of UBIQUITIN-PROTEIN LIGASES.
| Descriptor ID |
D044763
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| MeSH Number(s) |
D08.811.464.938.500
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| Concept/Terms |
Ubiquitin-Conjugating Enzymes- Ubiquitin-Conjugating Enzymes
- Enzymes, Ubiquitin-Conjugating
- Ubiquitin Conjugating Enzymes
- Ubiquitin-Conjugating Enzyme E2
- E2, Ubiquitin-Conjugating Enzyme
- Enzyme E2, Ubiquitin-Conjugating
- Ubiquitin Conjugating Enzyme E2
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Below are MeSH descriptors whose meaning is more general than "Ubiquitin-Conjugating Enzymes".
Below are MeSH descriptors whose meaning is more specific than "Ubiquitin-Conjugating Enzymes".
This graph shows the total number of publications written about "Ubiquitin-Conjugating Enzymes" by people in this website by year, and whether "Ubiquitin-Conjugating Enzymes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 2 | 0 | 2 |
| 2010 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ubiquitin-Conjugating Enzymes" by people in Profiles.
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Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding. Arthritis Rheumatol. 2022 01; 74(1):163-173.
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Loss of the ubiquitin conjugating enzyme UBE2E3 induces cellular senescence. Redox Biol. 2018 07; 17:411-422.
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Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons. BMC Neurosci. 2015 Nov 13; 16:76.
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Identification of primary and secondary metabolites with phosphorus status-dependent abundance in Arabidopsis, and of the transcription factor PHR1 as a major regulator of metabolic changes during phosphorus limitation. Plant Cell Environ. 2015 Jan; 38(1):172-87.
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The ubiquitin-conjugating enzyme, UbcM2, is restricted to monoubiquitylation by a two-fold mechanism that involves backside residues of E2 and Lys48 of ubiquitin. Biochemistry. 2014 Jun 24; 53(24):4004-14.
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A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus. Genes Immun. 2012 Jul; 13(5):380-7.
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Expression and distribution of the class III ubiquitin-conjugating enzymes in the retina. Mol Vis. 2010 Nov 18; 16:2425-37.
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The ubiquitin-conjugating enzyme UbcM2 can regulate the stability and activity of the antioxidant transcription factor Nrf2. J Biol Chem. 2010 Jul 23; 285(30):23064-74.
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The rat Apg3p/Aut1p homolog is upregulated by ischemic preconditioning in the retina. Mol Vis. 2006 Oct 26; 12:1292-302.
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Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105. Oncogene. 2006 Mar 02; 25(9):1330-9.