"Silymarin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mixture of flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum. It consists primarily of silybin and its isomers, silicristin and silidianin. Silymarin displays antioxidant and membrane stabilizing activity. It protects various tissues and organs against chemical injury, and shows potential as an antihepatoxic agent.
| Descriptor ID |
D012838
|
| MeSH Number(s) |
D03.383.663.283.266.450.268.777 D03.633.100.150.266.450.268.777
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Silymarin".
Below are MeSH descriptors whose meaning is more specific than "Silymarin".
This graph shows the total number of publications written about "Silymarin" by people in this website by year, and whether "Silymarin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Silymarin" by people in Profiles.
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Silibinin-mediated metabolic reprogramming attenuates pancreatic cancer-induced cachexia and tumor growth. Oncotarget. 2015 Dec 01; 6(38):41146-61.
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Identification and initial SAR of silybin: an Hsp90 inhibitor. Bioorg Med Chem Lett. 2011 May 01; 21(9):2659-64.
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Synergy in a medicinal plant: antimicrobial action of berberine potentiated by 5'-methoxyhydnocarpin, a multidrug pump inhibitor. Proc Natl Acad Sci U S A. 2000 Feb 15; 97(4):1433-7.