"Wnt Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
| Descriptor ID |
D051153
|
| MeSH Number(s) |
D12.776.467.984 D23.529.984
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Wnt Proteins".
Below are MeSH descriptors whose meaning is more specific than "Wnt Proteins".
This graph shows the total number of publications written about "Wnt Proteins" by people in this website by year, and whether "Wnt Proteins" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 2 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2013 | 2 | 2 | 4 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Wnt Proteins" by people in Profiles.
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Transcriptomic and Immunohistochemical Analysis of Progressive Keratoconus Reveal Altered WNT10A in Epithelium and Bowman's Layer. Invest Ophthalmol Vis Sci. 2021 05 03; 62(6):16.
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Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/ß-Catenin Signaling. Cell Rep. 2018 10 16; 25(3):571-584.e5.
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Transgenic expression of a canonical Wnt inhibitor, kallistatin, is associated with decreased circulating CD19+ B lymphocytes in the peripheral blood. Int J Hematol. 2017 Jun; 105(6):748-757.
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Increased Wnt and Notch signaling: a clue to the renal disease in Schimke immuno-osseous dysplasia? Orphanet J Rare Dis. 2016 11 05; 11(1):149.
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Interaction of PPARa With the Canonic Wnt Pathway in the Regulation of Renal Fibrosis. Diabetes. 2016 Dec; 65(12):3730-3743.
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A synthetic niche for nephron progenitor cells. Dev Cell. 2015 Jul 27; 34(2):229-41.
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Expression of the wnt gene complement in a spiral-cleaving embryo and trochophore larva. Int J Dev Biol. 2014; 58(6-8):563-73.
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CHD8 is an independent prognostic indicator that regulates Wnt/ß-catenin signaling and the cell cycle in gastric cancer. Oncol Rep. 2013 Sep; 30(3):1137-42.
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Utility of a bacterial infection model to study epithelial-mesenchymal transition, mesenchymal-epithelial transition or tumorigenesis. Oncogene. 2014 May 15; 33(20):2639-54.
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Carriers of a novel frame-shift insertion in WNT16a possess elevated pancreatic expression of TCF7L2. BMC Genet. 2013 Apr 23; 14:28.