"TRPP Cation Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subgroup of TRP cation channels that are widely expressed in various cell types. Defects are associated with POLYCYSTIC KIDNEY DISEASES.
| Descriptor ID |
D050396
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| MeSH Number(s) |
D12.776.157.530.400.150.900 D12.776.157.530.400.901.777 D12.776.543.585.400.150.900 D12.776.543.585.400.901.777
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "TRPP Cation Channels".
Below are MeSH descriptors whose meaning is more specific than "TRPP Cation Channels".
This graph shows the total number of publications written about "TRPP Cation Channels" by people in this website by year, and whether "TRPP Cation Channels" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 4 | 0 | 4 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "TRPP Cation Channels" by people in Profiles.
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Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathway. Life Sci Alliance. 2020 09; 3(9).
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Polycystins as components of large multiprotein complexes of polycystin interactors. Cell Signal. 2020 08; 72:109640.
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Polycystic Kidney Disease. Compr Physiol. 2017 06 18; 7(3):945-975.
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The Sorting Nexin 3 Retromer Pathway Regulates the Cell Surface Localization and Activity of a Wnt-Activated Polycystin Channel Complex. J Am Soc Nephrol. 2017 Oct; 28(10):2973-2984.
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The polycystin complex mediates Wnt/Ca(2+) signalling. Nat Cell Biol. 2016 07; 18(7):752-764.
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Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1. Hum Mol Genet. 2012 Dec 15; 21(26):5456-71.
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Function and regulation of TRPP2 at the plasma membrane. Am J Physiol Renal Physiol. 2009 Jul; 297(1):F1-9.
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Mutant polycystin-2 induces proliferation in primary rat tubular epithelial cells in a STAT-1/p21-independent fashion accompanied instead by alterations in expression of p57KIP2 and Cdk2. BMC Nephrol. 2008 Aug 25; 9:10.
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Identification and functional characterization of an N-terminal oligomerization domain for polycystin-2. J Biol Chem. 2008 Oct 17; 283(42):28471-9.
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Activation of TRPP2 through mDia1-dependent voltage gating. EMBO J. 2008 May 07; 27(9):1345-56.