"TRPC6 Cation Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A non-selective, calcium permeant TRPC cation channel that contains four ANKYRIN REPEATS and is activated by DIACYLGLYCEROL independently of PROTEIN KINASE C. It is expressed in placenta, lung, spleen, ovary and the small intestine, as well as by PODOCYTES in the kidney glomerulus. Mutations in the TRPC6 gene are associated with FOCAL SEGMENTAL GLOMERULOSCLEROSIS type 2.
| Descriptor ID |
D000074287
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| MeSH Number(s) |
D12.776.157.530.400.150.850 D12.776.157.530.400.901.500.500 D12.776.543.550.450.150.900 D12.776.543.585.400.150.850 D12.776.543.585.400.901.500.500
|
| Concept/Terms |
TRPC6 Cation Channel- TRPC6 Cation Channel
- Cation Channel, TRPC6
- Channel, TRPC6 Cation
- Transient Receptor Potential Cation Channel Subfamily C, Member 6
- TRPC6
|
Below are MeSH descriptors whose meaning is more general than "TRPC6 Cation Channel".
Below are MeSH descriptors whose meaning is more specific than "TRPC6 Cation Channel".
This graph shows the total number of publications written about "TRPC6 Cation Channel" by people in this website by year, and whether "TRPC6 Cation Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "TRPC6 Cation Channel" by people in Profiles.
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Store-operated calcium entry contributes to abnormal Ca²? signalling in dystrophic mdx mouse myoblasts. Arch Biochem Biophys. 2015 Mar 01; 569:1-9.
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Age-related autoregulatory dysfunction and cerebromicrovascular injury in mice with angiotensin II-induced hypertension. J Cereb Blood Flow Metab. 2013 Nov; 33(11):1732-42.