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Lawrence Ian Rothblum

TitleProf
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentCell Biology
AddressBMSB 553
940 Stanton L Young Blvd
Oklahoma City OK 73104
Phone405/271-2377
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    Collapse Research 
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    R01GM037252     (ROTHBLUM, LAWRENCE I)Jul 1, 1986 - Jun 30, 1990
    NIH
    CHARACTERIZATION OF ENHANCER IN RIBOSOMAL DNA
    Role: Principal Investigator

    R01HL047638     (ROTHBLUM, LAWRENCE I)Feb 1, 1992 - Jan 31, 1997
    NIH
    REGULATION OF RRNA SYNTHESIS DURING CARDIAC HYPERTROPHY
    Role: Principal Investigator

    R01GM046991     (ROTHBLUM, LAWRENCE I)Feb 1, 1992 - Jun 30, 2001
    NIH
    TRANSCRIPTION OF RAT RIBOSOMAL DNA
    Role: Principal Investigator

    R01GM069841     (ROTHBLUM, LAWRENCE I)Sep 1, 2005 - Aug 31, 2010
    NIH
    Protein interactions and initiation by RNA polymerase I
    Role: Principal Investigator

    R01HL077814     (ROTHBLUM, LAWRENCE I)Apr 1, 2006 - Mar 31, 2011
    NIH
    Ribosome Biogenesis: A Molecular Checkpoint for Cardiac Hypertrophy
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. McNamar R, Rothblum K, Rothblum LI. The Mammalian and Yeast A49 and A34 Heterodimers: Homologous but Not the Same. Genes (Basel). 2021 Apr 22; 12(5). PMID: 33921963.
      Citations:    Fields:    
    2. Knutson BA, McNamar R, Rothblum LI. Dynamics of the RNA polymerase I TFIIF/TFIIE-like subcomplex: a mini-review. Biochem Soc Trans. 2020 10 30; 48(5):1917-1927. PMID: 32915199.
      Citations: 1     Fields:    
    3. McNamar R, Abu-Adas Z, Rothblum K, Knutson BA, Rothblum LI. Conditional depletion of the RNA polymerase I subunit PAF53 reveals that it is essential for mitosis and enables identification of functional domains. J Biol Chem. 2019 12 27; 294(52):19907-19922. PMID: 31727736.
      Citations: 1     Fields:    Translation:AnimalsCells
    4. Rothblum LI, Rothblum K, Chang E. PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression. Gene. 2017 May 15; 612:55-60. PMID: 28042089.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    5. Hung SS, Lesmana A, Peck A, Lee R, Tchoubrieva E, Hannan KM, Lin J, Sheppard KE, Jastrzebski K, Quinn LM, Rothblum LI, Pearson RB, Hannan RD, Sanij E. Cell cycle and growth stimuli regulate different steps of RNA polymerase I transcription. Gene. 2017 May 15; 612:36-48. PMID: 27989772.
      Citations: 5     Fields:    Translation:AnimalsCells
    6. Sanij E, Diesch J, Lesmana A, Poortinga G, Hein N, Lidgerwood G, Cameron DP, Ellul J, Goodall GJ, Wong LH, Dhillon AS, Hamdane N, Rothblum LI, Pearson RB, Haviv I, Moss T, Hannan RD. A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes. Genome Res. 2015 Feb; 25(2):201-12. PMID: 25452314.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    7. Penrod Y, Rothblum K, Cavanaugh A, Rothblum LI. Regulation of the association of the PAF53/PAF49 heterodimer with RNA polymerase I. Gene. 2015 Feb 01; 556(1):61-7. PMID: 25225125.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    8. Rothblum K, Hu Q, Penrod Y, Rothblum LI. Selective inhibition of rDNA transcription by a small-molecule peptide that targets the interface between RNA polymerase I and Rrn3. Mol Cancer Res. 2014 Nov; 12(11):1586-96. PMID: 25033839.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    9. Stepanchick A, Zhi H, Cavanaugh AH, Rothblum K, Schneider DA, Rothblum LI. DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription. J Biol Chem. 2013 Mar 29; 288(13):9135-44. PMID: 23393135.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    10. Hannan KM, Sanij E, Rothblum LI, Hannan RD, Pearson RB. Dysregulation of RNA polymerase I transcription during disease. Biochim Biophys Acta. 2013 Mar-Apr; 1829(3-4):342-60. PMID: 23153826.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    11. Penrod Y, Rothblum K, Rothblum LI. Characterization of the interactions of mammalian RNA polymerase I associated proteins PAF53 and PAF49. Biochemistry. 2012 Aug 21; 51(33):6519-26. PMID: 22849406.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    12. DuRose JB, Scheuner D, Kaufman RJ, Rothblum LI, Niwa M. Phosphorylation of eukaryotic translation initiation factor 2alpha coordinates rRNA transcription and translation inhibition during endoplasmic reticulum stress. Mol Cell Biol. 2009 Aug; 29(15):4295-307. PMID: 19470760.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    13. Sanij E, Poortinga G, Sharkey K, Hung S, Holloway TP, Quin J, Robb E, Wong LH, Thomas WG, Stefanovsky V, Moss T, Rothblum L, Hannan KM, McArthur GA, Pearson RB, Hannan RD. UBF levels determine the number of active ribosomal RNA genes in mammals. J Cell Biol. 2008 Dec 29; 183(7):1259-74. PMID: 19103806.
      Citations: 71     Fields:    Translation:AnimalsCells
    14. Cavanaugh AH, Evans A, Rothblum LI. Mammalian Rrn3 is required for the formation of a transcription competent preinitiation complex containing RNA polymerase I. Gene Expr. 2008; 14(3):131-47. PMID: 18590050.
      Citations: 12     Fields:    Translation:AnimalsCells
    15. Zhang PL, Rothblum LI, Han WK, Blasick TM, Potdar S, Bonventre JV. Kidney injury molecule-1 expression in transplant biopsies is a sensitive measure of cell injury. Kidney Int. 2008 Mar; 73(5):608-14. PMID: 18160964.
      Citations: 42     Fields:    Translation:HumansAnimals
    16. Cheung JY, Rothblum LI, Moorman JR, Tucker AL, Song J, Ahlers BA, Carl LL, Wang J, Zhang XQ. Regulation of cardiac Na+/Ca2+ exchanger by phospholemman. Ann N Y Acad Sci. 2007 Mar; 1099:119-34. PMID: 17446450.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    17. Wang J, Zhang XQ, Ahlers BA, Carl LL, Song J, Rothblum LI, Stahl RC, Carey DJ, Cheung JY. Cytoplasmic tail of phospholemman interacts with the intracellular loop of the cardiac Na+/Ca2+ exchanger. J Biol Chem. 2006 Oct 20; 281(42):32004-14. PMID: 16921169.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    18. Huang S, Rothblum LI, Chen D. Ribosomal chromatin organization. Biochem Cell Biol. 2006 Aug; 84(4):444-9. PMID: 16936818.
      Citations: 10     Fields:    Translation:AnimalsCells
    19. Tucker AL, Song J, Zhang XQ, Wang J, Ahlers BA, Carl LL, Mounsey JP, Moorman JR, Rothblum LI, Cheung JY. Altered contractility and [Ca2+]i homeostasis in phospholemman-deficient murine myocytes: role of Na+/Ca2+ exchange. . 2006 Nov; 291(5):H2199-209. PMID: 16751288.
      Citations:    
    20. Zhang XQ, Ahlers BA, Tucker AL, Song J, Wang J, Moorman JR, Mounsey JP, Carl LL, Rothblum LI, Cheung JY. Phospholemman inhibition of the cardiac Na+/Ca2+ exchanger. Role of phosphorylation. J Biol Chem. 2006 Mar 24; 281(12):7784-92. PMID: 16434394.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    21. Vecchio L, Soldani C, Bottone MG, Malatesta M, Martin TE, Rothblum LI, Pellicciari C, Biggiogera M. DADLE induces a reversible hibernation-like state in HeLa cells. Histochem Cell Biol. 2006 Jan; 125(1-2):193-201. PMID: 16235044.
      Citations: 14     Fields:    Translation:HumansCells
    22. Zhang XQ, Moorman JR, Ahlers BA, Carl LL, Lake DE, Song J, Mounsey JP, Tucker AL, Chan YM, Rothblum LI, Stahl RC, Carey DJ, Cheung JY. Phospholemman overexpression inhibits Na+-K+-ATPase in adult rat cardiac myocytes: relevance to decreased Na+ pump activity in postinfarction myocytes. J Appl Physiol (1985). 2006 Jan; 100(1):212-20. PMID: 16195392.
      Citations: 24     Fields:    Translation:AnimalsCells
    23. Ahlers BA, Zhang XQ, Moorman JR, Rothblum LI, Carl LL, Song J, Wang J, Geddis LM, Tucker AL, Mounsey JP, Cheung JY. Identification of an endogenous inhibitor of the cardiac Na+/Ca2+ exchanger, phospholemman. J Biol Chem. 2005 May 20; 280(20):19875-82. PMID: 15774479.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    24. Ahlers BA, Song J, Wang J, Zhang XQ, Carl LL, Tadros GM, Rothblum LI, Cheung JY. Effects of sarcoplasmic reticulum Ca2+-ATPase overexpression in postinfarction rat myocytes. J Appl Physiol (1985). 2005 Jun; 98(6):2169-76. PMID: 15677742.
      Citations: 7     Fields:    Translation:AnimalsCells
    25. Song J, Zhang XQ, Ahlers BA, Carl LL, Wang J, Rothblum LI, Stahl RC, Mounsey JP, Tucker AL, Moorman JR, Cheung JY. Serine 68 of phospholemman is critical in modulation of contractility, [Ca2+]i transients, and Na+/Ca2+ exchange in adult rat cardiac myocytes. . 2005 May; 288(5):H2342-54. PMID: 15653756.
      Citations:    
    26. Cheung JY, Song J, Rothblum LI, Zhang XQ. Exercise training improves cardiac function postinfarction: special emphasis on recent controversies on na+/ca2+ exchanger. Exerc Sport Sci Rev. 2004 Jul; 32(3):83-9. PMID: 15243202.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    27. Song J, Zhang XQ, Wang J, Carl LL, Ahlers BA, Rothblum LI, Cheung JY. Sprint training improves contractility in postinfarction rat myocytes: role of Na+/Ca2+ exchange. J Appl Physiol (1985). 2004 Aug; 97(2):484-90. PMID: 15075297.
      Citations: 3     Fields:    Translation:AnimalsCells
    28. Mirza MA, Zhang XQ, Ahlers BA, Qureshi A, Carl LL, Song J, Tucker AL, Mounsey JP, Moorman JR, Rothblum LI, Zhang TS, Cheung JY. Effects of phospholemman downregulation on contractility and [Ca(2+)]i transients in adult rat cardiac myocytes. . 2004 Apr; 286(4):H1322-30. PMID: 14684371.
      Citations:    
    29. Hannan KM, Brandenburger Y, Jenkins A, Sharkey K, Cavanaugh A, Rothblum L, Moss T, Poortinga G, McArthur GA, Pearson RB, Hannan RD. mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF. Mol Cell Biol. 2003 Dec; 23(23):8862-77. PMID: 14612424.
      Citations: 165     Fields:    Translation:AnimalsCells
    30. Brandenburger Y, Arthur JF, Woodcock EA, Du XJ, Gao XM, Autelitano DJ, Rothblum LI, Hannan RD. Cardiac hypertrophy in vivo is associated with increased expression of the ribosomal gene transcription factor UBF. FEBS Lett. 2003 Jul 31; 548(1-3):79-84. PMID: 12885411.
      Citations: 5     Fields:    Translation:AnimalsCells
    31. Hirschler-Laszkiewicz I, Cavanaugh AH, Mirza A, Lun M, Hu Q, Smink T, Rothblum LI. Rrn3 becomes inactivated in the process of ribosomal DNA transcription. J Biol Chem. 2003 May 23; 278(21):18953-9. PMID: 12646563.
      Citations: 23     Fields:    Translation:AnimalsCells
    32. Dundr M, Hoffmann-Rohrer U, Hu Q, Grummt I, Rothblum LI, Phair RD, Misteli T. A kinetic framework for a mammalian RNA polymerase in vivo. Science. 2002 Nov 22; 298(5598):1623-6. PMID: 12446911.
      Citations: 165     Fields:    Translation:HumansAnimalsCells
    33. Zhang XQ, Qureshi A, Song J, Carl LL, Tian Q, Stahl RC, Carey DJ, Rothblum LI, Cheung JY. Phospholemman modulates Na+/Ca2+ exchange in adult rat cardiac myocytes. . 2003 Jan; 284(1):H225-33. PMID: 12388273.
      Citations:    
    34. Zhang XQ, Song J, Qureshi A, Rothblum LI, Carl LL, Tian Q, Cheung JY. Rescue of contractile abnormalities by Na+/Ca2+ exchanger overexpression in postinfarction rat myocytes. J Appl Physiol (1985). 2002 Dec; 93(6):1925-31. PMID: 12391043.
      Citations: 5     Fields:    Translation:AnimalsCells
    35. Song J, Zhang XQ, Carl LL, Qureshi A, Rothblum LI, Cheung JY. Overexpression of phospholemman alters contractility and [Ca(2+)](i) transients in adult rat myocytes. . 2002 Aug; 283(2):H576-83. PMID: 12124204.
      Citations:    
    36. Chu X, Cheung JY, Barber DL, Birnbaumer L, Rothblum LI, Conrad K, Abrasonis V, Chan YM, Stahl R, Carey DJ, Miller BA. Erythropoietin modulates calcium influx through TRPC2. J Biol Chem. 2002 Sep 13; 277(37):34375-82. PMID: 12167663.
      Citations: 18     Fields:    Translation:AnimalsCells
    37. Hu Q, Suzuki K, Hirschler-Laszkiewicz I, Rothblum LI. Paradoxical effect of eukaryotic expression vectors on reporters. Biotechniques. 2002 Jul; 33(1):74, 76, 78 passim. PMID: 12139260.
      Citations: 3     Fields:    Translation:AnimalsCells
    38. Tadros GM, Zhang XQ, Song J, Carl LL, Rothblum LI, Tian Q, Dunn J, Lytton J, Cheung JY. Effects of Na(+)/Ca(2+) exchanger downregulation on contractility and [Ca(2+)](i) transients in adult rat myocytes. . 2002 Oct; 283(4):H1616-26. PMID: 12234816.
      Citations:    
    39. Flynn BJ, Mian HS, Cera PJ, Kabler RL, Mowad JJ, Cavanaugh AH, Rothblum LI. Early molecular changes in bladder hypertrophy due to bladder outlet obstruction. Urology. 2002 Jun; 59(6):978-82. PMID: 12031398.
      Citations: 3     Fields:    Translation:Animals
    40. Cavanaugh AH, Hirschler-Laszkiewicz I, Hu Q, Dundr M, Smink T, Misteli T, Rothblum LI. Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis. J Biol Chem. 2002 Jul 26; 277(30):27423-32. PMID: 12015311.
      Citations: 40     Fields:    Translation:AnimalsCells
    41. Zhang XQ, Song J, Rothblum LI, Lun M, Wang X, Ding F, Dunn J, Lytton J, McDermott PJ, Cheung JY. Overexpression of Na+/Ca2+ exchanger alters contractility and SR Ca2+ content in adult rat myocytes. . 2001 Nov; 281(5):H2079-88. PMID: 11668069.
      Citations:    
    42. Stefanovsky VY, Pelletier G, Hannan R, Gagnon-Kugler T, Rothblum LI, Moss T. An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF. Mol Cell. 2001 Nov; 8(5):1063-73. PMID: 11741541.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    43. Hirschler-Laszkiewicz I, Cavanaugh A, Hu Q, Catania J, Avantaggiati ML, Rothblum LI. The role of acetylation in rDNA transcription. Nucleic Acids Res. 2001 Oct 15; 29(20):4114-24. PMID: 11600700.
      Citations: 34     Fields:    Translation:AnimalsCells
    44. Biggiogera M, Malatesta M, Abolhassani-Dadras S, Amalric F, Rothblum LI, Fakan S. Revealing the unseen: the organizer region of the nucleolus. J Cell Sci. 2001 Sep; 114(Pt 17):3199-205. PMID: 11590246.
      Citations: 9     Fields:    Translation:AnimalsCells
    45. Pelletier G, Stefanovsky VY, Faubladier M, Hirschler-Laszkiewicz I, Savard J, Rothblum LI, Côté J, Moss T. Competitive recruitment of CBP and Rb-HDAC regulates UBF acetylation and ribosomal transcription. Mol Cell. 2000 Nov; 6(5):1059-66. PMID: 11106745.
      Citations: 48     Fields:    Translation:AnimalsCells
    46. Hannan KM, Hannan RD, Smith SD, Jefferson LS, Lun M, Rothblum LI. Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1. Oncogene. 2000 Oct 12; 19(43):4988-99. PMID: 11042686.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    47. Hannan KM, Kennedy BK, Cavanaugh AH, Hannan RD, Hirschler-Laszkiewicz I, Jefferson LS, Rothblum LI. RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest. Oncogene. 2000 Jul 20; 19(31):3487-97. PMID: 10918607.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    48. Zhang LQ, Zhang XQ, Ng YC, Rothblum LI, Musch TI, Moore RL, Cheung JY. Sprint training normalizes Ca(2+) transients and SR function in postinfarction rat myocytes. J Appl Physiol (1985). 2000 Jul; 89(1):38-46. PMID: 10904033.
      Citations: 9     Fields:    Translation:AnimalsCells
    49. Cmarko D, Verschure PJ, Rothblum LI, Hernandez-Verdun D, Amalric F, van Driel R, Fakan S. Ultrastructural analysis of nucleolar transcription in cells microinjected with 5-bromo-UTP. Histochem Cell Biol. 2000 Mar; 113(3):181-7. PMID: 10817672.
      Citations: 24     Fields:    Translation:HumansCells
    50. Hannan RD, Cavanaugh A, Hempel WM, Moss T, Rothblum L. Identification of a mammalian RNA polymerase I holoenzyme containing components of the DNA repair/replication system. Nucleic Acids Res. 1999 Sep 15; 27(18):3720-7. PMID: 10471742.
      Citations: 22     Fields:    Translation:AnimalsCells
    51. Miller BA, Barber DL, Bell LL, Beattie BK, Zhang MY, Neel BG, Yoakim M, Rothblum LI, Cheung JY. Identification of the erythropoietin receptor domain required for calcium channel activation. J Biol Chem. 1999 Jul 16; 274(29):20465-72. PMID: 10400674.
      Citations: 14     Fields:    Translation:AnimalsCells
    52. Hannan R, Stefanovsky V, Arino T, Rothblum L, Moss T. Cellular regulation of ribosomal DNA transcription:both rat and Xenopus UBF1 stimulate rDNA transcription in 3T3 fibroblasts. Nucleic Acids Res. 1999 Feb 15; 27(4):1205-13. PMID: 9927757.
      Citations: 13     Fields:    Translation:AnimalsCells
    53. Klein C, Cheutin T, O'Donohue MF, Rothblum L, Kaplan H, Beorchia A, Lucas L, Héliot L, Ploton D. The three-dimensional study of chromosomes and upstream binding factor-immunolabeled nucleolar organizer regions demonstrates their nonrandom spatial arrangement during mitosis. Mol Biol Cell. 1998 Nov; 9(11):3147-59. PMID: 9802903.
      Citations: 5     Fields:    Translation:HumansCells
    54. Hannan KM, Rothblum LI, Jefferson LS. Regulation of ribosomal DNA transcription by insulin. Am J Physiol. 1998 07; 275(1):C130-8. PMID: 9688843.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    55. Hannan KM, Hannan RD, Rothblum LI. Transcription by RNA polymerase I. Front Biosci. 1998 Mar 26; 3:d376-98. PMID: 9514985.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    56. Hannan RD, Hempel WM, Cavanaugh A, Arino T, Dimitrov SI, Moss T, Rothblum L. Affinity purification of mammalian RNA polymerase I. Identification of an associated kinase. J Biol Chem. 1998 Jan 09; 273(2):1257-67. PMID: 9422795.
      Citations: 29     Fields:    Translation:AnimalsCells
    57. Ridsdale RA, Semotok JL, Larson DE, Rothblum LI, Harauz G. Topology of recombinant rat upstream binding factor. Biochem Cell Biol. 1998; 76(4):649-55. PMID: 10099786.
      Citations:    Fields:    Translation:AnimalsCells
    58. Carey DJ, Conner K, Asundi VK, O'Mahony DJ, Stahl RC, Showalter L, Cizmeci-Smith G, Hartman J, Rothblum LI. cDNA cloning, genomic organization, and in vivo expression of rat N-syndecan. J Biol Chem. 1997 Jan 31; 272(5):2873-9. PMID: 9006931.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    59. Kabler RL, Srinivasan A, Taylor LJ, Mowad J, Rothblum LI, Cavanaugh AH. Androgen regulation of ribosomal RNA synthesis in LNCaP cells and rat prostate. J Steroid Biochem Mol Biol. 1996 Dec; 59(5-6):431-9. PMID: 9010348.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    60. Hannan RD, Stefanovsky V, Taylor L, Moss T, Rothblum LI. Overexpression of the transcription factor UBF1 is sufficient to increase ribosomal DNA transcription in neonatal cardiomyocytes: implications for cardiac hypertrophy. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8750-5. PMID: 8710943.
      Citations: 20     Fields:    Translation:AnimalsCells
    61. Chao JC, Wan XS, Engelsberg BN, Rothblum LI, Billings PC. Intracellular distribution of HMG1, HMG2 and UBF change following treatment with cisplatin. Biochim Biophys Acta. 1996 Jun 07; 1307(2):213-9. PMID: 8679707.
      Citations: 3     Fields:    Translation:HumansCells
    62. Neil KJ, Ridsdale RA, Rutherford B, Taylor L, Larson DE, Glibetic M, Rothblum LI, Harauz G. Structure of recombinant rat UBF by electron image analysis and homology modelling. Nucleic Acids Res. 1996 Apr 15; 24(8):1472-80. PMID: 8628680.
      Citations: 3     Fields:    Translation:AnimalsCells
    63. Luyken J, Hannan RD, Cheung JY, Rothblum LI. Regulation of rDNA transcription during endothelin-1-induced hypertrophy of neonatal cardiomyocytes. Hyperphosphorylation of upstream binding factor, an rDNA transcription factor. Circ Res. 1996 Mar; 78(3):354-61. PMID: 8593693.
      Citations: 11     Fields:    Translation:AnimalsCells
    64. Hannan RD, Luyken J, Rothblum LI. Regulation of ribosomal DNA transcription during contraction-induced hypertrophy of neonatal cardiomyocytes. J Biol Chem. 1996 Feb 09; 271(6):3213-20. PMID: 8621723.
      Citations: 20     Fields:    Translation:AnimalsCells
    65. Hempel WM, Cavanaugh AH, Hannan RD, Taylor L, Rothblum LI. The species-specific RNA polymerase I transcription factor SL-1 binds to upstream binding factor. Mol Cell Biol. 1996 Feb; 16(2):557-63. PMID: 8552083.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    66. Hershey JC, Hautmann M, Thompson MM, Rothblum LI, Haystead TA, Owens GK. Angiotensin II-induced hypertrophy of rat vascular smooth muscle is associated with increased 18 S rRNA synthesis and phosphorylation of the rRNA transcription factor, upstream binding factor. J Biol Chem. 1995 Oct 20; 270(42):25096-101. PMID: 7559641.
      Citations: 9     Fields:    Translation:AnimalsCells
    67. Hannan RD, Rothblum LI. Regulation of ribosomal DNA transcription during neonatal cardiomyocyte hypertrophy. Cardiovasc Res. 1995 Oct; 30(4):501-10. PMID: 8574998.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    68. Hannan RD, Luyken J, Rothblum LI. Regulation of rDNA transcription factors during cardiomyocyte hypertrophy induced by adrenergic agents. J Biol Chem. 1995 Apr 07; 270(14):8290-7. PMID: 7713937.
      Citations: 9     Fields:    Translation:AnimalsCells
    69. Cavanaugh AH, Hempel WM, Taylor LJ, Rogalsky V, Todorov G, Rothblum LI. Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product. Nature. 1995 Mar 09; 374(6518):177-80. PMID: 7877691.
      Citations: 106     Fields:    Translation:HumansAnimalsCells
    70. Glibetic M, Taylor L, Larson D, Hannan R, Sells B, Rothblum L. The RNA polymerase I transcription factor UBF is the product of a primary response gene. J Biol Chem. 1995 Mar 03; 270(9):4209-12. PMID: 7876178.
      Citations: 10     Fields:    Translation:AnimalsCells
    71. Jiménez-García LF, Segura-Valdez ML, Ochs RL, Rothblum LI, Hannan R, Spector DL. Nucleologenesis: U3 snRNA-containing prenucleolar bodies move to sites of active pre-rRNA transcription after mitosis. Mol Biol Cell. 1994 Sep; 5(9):955-66. PMID: 7841523.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    72. Larson DE, Xie W, Glibetic M, O'Mahony D, Sells BH, Rothblum LI. Coordinated decreases in rRNA gene transcription factors and rRNA synthesis during muscle cell differentiation. Proc Natl Acad Sci U S A. 1993 Sep 01; 90(17):7933-6. PMID: 8396256.
      Citations: 18     Fields:    Translation:AnimalsCells
    73. Glibetic M, Larson DE, Rothblum LI, Sells BH. Dexamethasone stimulates rRNA gene transcription in rat myoblasts. Mol Cell Endocrinol. 1993 Aug; 94(2):243-52. PMID: 8224527.
      Citations:    Fields:    Translation:HumansAnimalsCells
    74. Schworer CM, Rothblum LI, Thekkumkara TJ, Singer HA. Identification of novel isoforms of the delta subunit of Ca2+/calmodulin-dependent protein kinase II. Differential expression in rat brain and aorta. J Biol Chem. 1993 Jul 05; 268(19):14443-9. PMID: 8390994.
      Citations: 51     Fields:    Translation:AnimalsCells
    75. Smith SD, O'Mahony DJ, Kinsella BT, Rothblum LI. Transcription from the rat 45S ribosomal DNA promoter does not require the factor UBF. Gene Expr. 1993; 3(3):229-36. PMID: 8019125.
      Citations: 22     Fields:    Translation:AnimalsCells
    76. Xie W, Rothblum LI. rDNA transcription and cardiac hypertrophy. Trends Cardiovasc Med. 1993 Jan-Feb; 3(1):7-11. PMID: 21244964.
      Citations: 1     Fields:    
    77. Xie W, O'Mahony DJ, Smith SD, Lowe D, Rothblum LI. Analysis of the rat ribosomal DNA promoter: characterization of linker-scanning mutants and of the binding of UBF. Nucleic Acids Res. 1992 Apr 11; 20(7):1587-92. PMID: 1579451.
      Citations: 5     Fields:    Translation:AnimalsCells
    78. O'Mahony DJ, Smith SD, Xie W, Rothblum LI. Analysis of the phosphorylation, DNA-binding and dimerization properties of the RNA polymerase I transcription factors UBF1 and UBF2. Nucleic Acids Res. 1992 Mar 25; 20(6):1301-8. PMID: 1561086.
      Citations: 42     Fields:    Translation:AnimalsCells
    79. Xie WQ, Rothblum LI. Domains of the rat rDNA promoter must be aligned stereospecifically. Mol Cell Biol. 1992 Mar; 12(3):1266-75. PMID: 1545808.
      Citations: 10     Fields:    Translation:AnimalsCells
    80. O'Mahony DJ, Xie WQ, Smith SD, Singer HA, Rothblum LI. Differential phosphorylation and localization of the transcription factor UBF in vivo in response to serum deprivation. In vitro dephosphorylation of UBF reduces its transactivation properties. J Biol Chem. 1992 Jan 05; 267(1):35-8. PMID: 1730600.
      Citations: 57     Fields:    Translation:AnimalsCells
    81. Xie WQ, Rothblum LI. Rapid, small-scale RNA isolation from tissue culture cells. Biotechniques. 1991 Sep; 11(3):324, 326-7. PMID: 1718328.
      Citations: 38     Fields:    Translation:AnimalsCells
    82. Xie WQ, O'Mahony DJ, Smith SD, Rothblum L. Complementary in vivo and in vitro analyses of the interactions between the cis-acting elements of the rat rDNA promoter. Mol Cell Biochem. 1991 May 29-Jun 12; 104(1-2):127-35. PMID: 1921991.
      Citations: 5     Fields:    Translation:AnimalsCells
    83. O'Mahony DJ, Rothblum LI. Identification of two forms of the RNA polymerase I transcription factor UBF. Proc Natl Acad Sci U S A. 1991 Apr 15; 88(8):3180-4. PMID: 2014238.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    84. Pikaard CS, Smith SD, Reeder RH, Rothblum L. rUBF, an RNA polymerase I transcription factor from rats, produces DNase I footprints identical to those produced by xUBF, its homolog from frogs. Mol Cell Biol. 1990 Jul; 10(7):3810-2. PMID: 2355924.
      Citations: 31     Fields:    Translation:AnimalsCells
    85. Smith SD, Oriahi E, Lowe D, Yang-Yen HF, O'Mahony D, Rose K, Chen K, Rothblum LI. Characterization of factors that direct transcription of rat ribosomal DNA. Mol Cell Biol. 1990 Jun; 10(6):3105-16. PMID: 2342470.
      Citations: 52     Fields:    Translation:AnimalsCells
    86. Smith SD, Oriahi E, Yang-Yen HF, Xie WQ, Chen C, Rothblum LI. Interaction of RNA polymerase I transcription factors with a promoter in the nontranscribed spacer of rat ribosomal DNA. Nucleic Acids Res. 1990 Apr 11; 18(7):1677-85. PMID: 2336355.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    87. McDermott PJ, Rothblum LI, Smith SD, Morgan HE. Accelerated rates of ribosomal RNA synthesis during growth of contracting heart cells in culture. J Biol Chem. 1989 Oct 25; 264(30):18220-7. PMID: 2808374.
      Citations: 13     Fields:    Translation:AnimalsCells
    88. Jiménez-García LF, Rothblum LI, Busch H, Ochs RL. Nucleologenesis: use of non-isotopic in situ hybridization and immunocytochemistry to compare the localization of rDNA and nucleolar proteins during mitosis. Biol Cell. 1989; 65(3):239-46. PMID: 2752212.
      Citations: 19     Fields:    Translation:AnimalsCells
    89. Yang-Yen HF, Rothblum LI. Purification and characterization of a high-mobility-group-like DNA-binding protein that stimulates rRNA synthesis in vitro. Mol Cell Biol. 1988 Aug; 8(8):3406-14. PMID: 3211145.
      Citations: 30     Fields:    Translation:AnimalsCells
    90. Smith HC, Rothblum LI. Ribosomal DNA sequences attached to the nuclear matrix. Biochem Genet. 1987 Dec; 25(11-12):863-79. PMID: 3450275.
      Citations: 8     Fields:    Translation:AnimalsCells
    91. Cassidy B, Haglund R, Rothblum LI. Regions upstream from the core promoter of the rat ribosomal gene are required for the formation of a stable transcription initiation complex by RNA polymerase I in vitro. Biochim Biophys Acta. 1987 Jul 14; 909(2):133-44. PMID: 3593729.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    92. Cassidy BG, Yang-Yen HF, Rothblum LI. Additional RNA polymerase I initiation site within the nontranscribed spacer region of the rat rRNA gene. Mol Cell Biol. 1987 Jul; 7(7):2388-96. PMID: 3614195.
      Citations: 28     Fields:    Translation:AnimalsCells
    93. Haglund RE, Rothblum LI. Isolation, fractionation and reconstitution of a nuclear extract capable of transcribing ribosomal DNA. Mol Cell Biochem. 1987 Jan; 73(1):11-20. PMID: 3807897.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    94. Cassidy BG, Yang-Yen HF, Rothblum LI. Transcriptional role for the nontranscribed spacer of rat ribosomal DNA. Mol Cell Biol. 1986 Aug; 6(8):2766-73. PMID: 3023948.
      Citations: 21     Fields:    Translation:AnimalsCells
    95. Yang-Yen HF, Subrahmanyam CS, Cassidy B, Rothblum LI. Characterization of rat ribosomal DNA II. identification of the highly repetitive DNA in the 3' non-transcribed spacer. J Mol Biol. 1985 Aug 05; 184(3):389-98. PMID: 3862875.
      Citations: 9     Fields:    Translation:AnimalsCells
    96. Parker DL, Mroczka DL, Rothblum LI. Amplified DNA of the Novikoff hepatoma nucleolus is arranged in a 7.3-kilobase tandem repeat. Biochemistry. 1985 Jul 16; 24(15):4229-33. PMID: 2996594.
      Citations: 1     Fields:    Translation:AnimalsCells
    97. Kurl RN, Rothblum LI, Jacob ST. A purified fraction containing RNA polymerase I that can accurately transcribe rat ribosomal RNA gene. Proc Natl Acad Sci U S A. 1984 Nov; 81(21):6672-5. PMID: 6593724.
      Citations: 12     Fields:    Translation:AnimalsCells
    98. Mroczka DL, Cassidy B, Busch H, Rothblum LI. Characterization of rat ribosomal DNA. The highly repetitive sequences that flank the ribosomal RNA transcription unit are homologous and contain RNA polymerase III transcription initiation sites. J Mol Biol. 1984 Mar 25; 174(1):141-62. PMID: 6716475.
      Citations: 20     Fields:    Translation:AnimalsCells
    99. Reddy R, Rothblum LI, Subrahmanyam CS, Liu MH, Henning D, Cassidy B, Busch H. The nucleotide sequence of 8 S RNA bound to preribosomal RNA of Novikoff hepatoma. The 5'-end of 8 S RNA is 5.8 S RNA. J Biol Chem. 1983 Jan 10; 258(1):584-9. PMID: 6401296.
      Citations: 10     Fields:    Translation:AnimalsCells
    100. Rothblum LI, Reddy R, Cassidy B. Transcription initiation site of rat ribosomal DNA. Nucleic Acids Res. 1982 Nov 25; 10(22):7345-62. PMID: 6296773.
      Citations: 42     Fields:    Translation:AnimalsCells
    101. Cassidy BG, Subrahmanyan CS, Rothblum LI. The nucleotide sequence of the 5' region of rat 18S rDNA and adjoining spacer. Biochem Biophys Res Commun. 1982 Aug 31; 107(4):1571-6. PMID: 6753847.
      Citations: 5     Fields:    Translation:AnimalsCells
    102. Subrahmanyam CS, Cassidy B, Busch H, Rothblum LI. Nucleotide sequence of the region between the 18S rRNA sequence and the 28S rRNA sequence of rat ribosomal DNA. Nucleic Acids Res. 1982 Jun 25; 10(12):3667-80. PMID: 6287418.
      Citations: 36     Fields:    Translation:AnimalsCells
    103. Rothblum LI, Parker DL, Cassidy B. Isolation and characterization of rat ribosomal DNA clones. Gene. 1982 Jan; 17(1):75-7. PMID: 6281138.
      Citations: 11     Fields:    Translation:AnimalsCells
    104. Parker DL, Busch H, Rothblum LI. Cloning and characterization of a highly reiterated 5.8-kilobase pair nucleolar EcoRI DNA fragment found in Novikoff hepatoma ascites cells. Biochemistry. 1981 Feb 17; 20(4):762-5. PMID: 6260140.
      Citations:    Fields:    Translation:AnimalsCells
    105. Hubbell HR, Rothblum LI, Hsu TC. Identification of a silver binding protein associated with the cytological silver staining of actively transcribing nucleolar regions. Cell Biol Int Rep. 1979 Oct; 3(7):615-22. PMID: 93980.
      Citations: 25     Fields:    Translation:AnimalsCells
    106. Parker DL, Rothblum LI, Busch H. A 3.6-megadalton, highly repetitive Eco RI fragment in the genome of Novikoff hepatoma. Cancer Res. 1979 Apr; 39(4):1287-92. PMID: 421212.
      Citations:    Fields:    Translation:AnimalsCells
    107. Rao MS, Rothblum LI, Busch H. Presence of elongation factor 1 in nuclei and nucleoli of rat liver. Cell Biol Int Rep. 1978 Jan; 2(1):25-32. PMID: 630613.
      Citations: 2     Fields:    Translation:AnimalsCells
    108. Busch H, Ballal NR, Busch RK, Choi YC, Davis F, Goldknopf IL, Matsui SI, Rao MS, Rothblum LI. The nucleolus, a model for analysis of chromatin controls. Cold Spring Harb Symp Quant Biol. 1978; 42 Pt 2:665-83. PMID: 354852.
      Citations: 2     Fields:    Translation:AnimalsCells
    109. Rothblum LI, Mamrack PM, Kunkle HM, Olson MO, Busch H. Fractionation of nucleoli. Enzymatic and two-dimensional polyacrylamide gel electrophoretic analysis. Biochemistry. 1977 Oct 18; 16(21):4716-21. PMID: 199241.
      Citations: 11     Fields:    Translation:AnimalsCells
    110. Busch H, Ballal NR, Busch RK, Choi YC, Davis F, Goldknopf IL, Matsui SI, Rao MS, Rothblum LI. Controls of nucleolar function in cancer cells. Adv Exp Med Biol. 1977 May 22-24; 92:125-80. PMID: 345771.
      Citations:    Fields:    Translation:Cells
    111. Wu BC, Rao MS, Gupta KK, Rothblum LI, Mamrack PC, Busch H. Evidence for coupled synthesis of mRNA for ribosomal proteins and rRNA. Cell Biol Int Rep. 1977 Jan; 1(1):31-44. PMID: 205372.
      Citations: 2     Fields:    Translation:AnimalsCells
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