Retinal Pigment Epithelium
"Retinal Pigment Epithelium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
| Descriptor ID |
D055213
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| MeSH Number(s) |
A09.371.670.500 A09.371.729.887
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinal Pigment Epithelium".
Below are MeSH descriptors whose meaning is more specific than "Retinal Pigment Epithelium".
This graph shows the total number of publications written about "Retinal Pigment Epithelium" by people in this website by year, and whether "Retinal Pigment Epithelium" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 2 | 3 |
| 2012 | 6 | 1 | 7 |
| 2013 | 5 | 1 | 6 |
| 2014 | 4 | 2 | 6 |
| 2015 | 4 | 0 | 4 |
| 2016 | 2 | 5 | 7 |
| 2017 | 1 | 1 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 3 | 4 |
| 2020 | 1 | 3 | 4 |
| 2021 | 5 | 0 | 5 |
| 2022 | 1 | 2 | 3 |
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Below are the most recent publications written about "Retinal Pigment Epithelium" by people in Profiles.
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Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Patient With Fragile X Syndrome. J Pediatr Ophthalmol Strabismus. 2022 Jul-Aug; 59(4):e39-e41.
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Prph2 disease mutations lead to structural and functional defects in the RPE. FASEB J. 2022 05; 36(5):e22284.
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Deficiency of thyroid hormone receptor protects retinal pigment epithelium and photoreceptors from cell death in a mouse model of age-related macular degeneration. Cell Death Dis. 2022 Mar 21; 13(3):255.
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Deuterated docosahexaenoic acid protects against oxidative stress and geographic atrophy-like retinal degeneration in a mouse model with iron overload. Aging Cell. 2022 04; 21(4):e13579.
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Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration. FASEB J. 2021 12; 35(12):e22058.
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An Analysis of Metabolic Changes in the Retina and Retinal Pigment Epithelium of Aging Mice. Invest Ophthalmol Vis Sci. 2021 11 01; 62(14):20.
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ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium. J Biol Chem. 2021 10; 297(4):101185.
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ßA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells. Commun Biol. 2021 07 08; 4(1):850.
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Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina. Biochem Biophys Res Commun. 2021 03 19; 545:8-13.
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Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R). Invest Ophthalmol Vis Sci. 2021 02 01; 62(2):30.