Retinal Pigment Epithelium
"Retinal Pigment Epithelium" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The single layer of pigment-containing epithelial cells in the RETINA, situated closely to the tips (outer segments) of the RETINAL PHOTORECEPTOR CELLS. These epithelial cells are macroglia that perform essential functions for the photoreceptor cells, such as in nutrient transport, phagocytosis of the shed photoreceptor membranes, and ensuring retinal attachment.
| Descriptor ID |
D055213
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| MeSH Number(s) |
A09.371.670.500 A09.371.729.887
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Retinal Pigment Epithelium".
Below are MeSH descriptors whose meaning is more specific than "Retinal Pigment Epithelium".
This graph shows the total number of publications written about "Retinal Pigment Epithelium" by people in this website by year, and whether "Retinal Pigment Epithelium" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 2 | 1 | 3 |
| 2010 | 3 | 0 | 3 |
| 2011 | 2 | 2 | 4 |
| 2012 | 6 | 2 | 8 |
| 2013 | 4 | 2 | 6 |
| 2014 | 4 | 2 | 6 |
| 2015 | 4 | 0 | 4 |
| 2016 | 2 | 6 | 8 |
| 2017 | 3 | 1 | 4 |
| 2018 | 1 | 3 | 4 |
| 2019 | 1 | 4 | 5 |
| 2020 | 1 | 3 | 4 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Retinal Pigment Epithelium" by people in Profiles.
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Singh HD, Ma JX, Takahashi Y. Distinct roles of LRP5 and LRP6 in Wnt signaling regulation in the retina. Biochem Biophys Res Commun. 2021 03 19; 545:8-13.
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Cheng SY, Cipi J, Ma S, Hafler BP, Kanadia RN, Brush RS, Agbaga MP, Punzo C. Altered photoreceptor metabolism in mouse causes late stage age-related macular degeneration-like pathologies. Proc Natl Acad Sci U S A. 2020 06 09; 117(23):13094-13104.
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Rajala A, Soni K, Rajala RVS. Metabolic and Non-metabolic Roles of Pyruvate Kinase M2 Isoform in Diabetic Retinopathy. Sci Rep. 2020 05 04; 10(1):7456.
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Mursalin MH, Coburn PS, Livingston E, Miller FC, Astley R, Flores-Mireles AL, Callegan MC. Bacillus S-Layer-Mediated Innate Interactions During Endophthalmitis. Front Immunol. 2020; 11:215.
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Ma H, Yang F, Ding XQ. Inhibition of thyroid hormone signaling protects retinal pigment epithelium and photoreceptors from cell death in a mouse model of age-related macular degeneration. Cell Death Dis. 2020 01 13; 11(1):24.
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Kautzmann MI, Gordon WC, Jun B, Do KV, Matherne BJ, Fang Z, Bazan NG. Membrane-type frizzled-related protein regulates lipidome and transcription for photoreceptor function. FASEB J. 2020 01; 34(1):912-929.
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Do KV, Kautzmann MI, Jun B, Gordon WC, Nshimiyimana R, Yang R, Petasis NA, Bazan NG. Elovanoids counteract oligomeric ß-amyloid-induced gene expression and protect photoreceptors. Proc Natl Acad Sci U S A. 2019 11 26; 116(48):24317-24325.
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Muhammad F, Trivett A, Wang D, Lee DJ. Tissue-specific production of MicroRNA-155 inhibits melanocortin 5 receptor-dependent suppressor macrophages to promote experimental autoimmune uveitis. Eur J Immunol. 2019 11; 49(11):2074-2082.
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Wilkerson JL, Stiles MA, Gurley JM, Grambergs RC, Gu X, Elliott MH, Proia RL, Mandal NA. Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina. Mol Neurobiol. 2019 Oct; 56(10):7188-7207.
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Seibert M, Krüger M, Watson NA, Sen O, Daum JR, Slotman JA, Braun T, Houtsmuller AB, Gorbsky GJ, Jacob R, Kracht M, Higgins JMG, Schmitz ML. CDK1-mediated phosphorylation at H2B serine 6 is required for mitotic chromosome segregation. J Cell Biol. 2019 04 01; 218(4):1164-1181.