"Cytochrome P-450 CYP1B1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytochrome P450 aryl hydrocarbon hydroxylase that has specificity for ESTROGENS which it converts into 4-hydroxy estrogens. CYP1B1 has been shown to be physiologically important for FETAL DEVELOPMENT with mutations in the CYP1B1 gene resulting in congenital forms of GLAUCOMA and Peter's anomaly.
| Descriptor ID |
D065633
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| MeSH Number(s) |
D08.244.453.005.500 D08.244.453.100.875 D08.811.682.690.708.170.010.500 D08.811.682.690.708.170.020.875 D12.776.422.220.453.010.500 D12.776.422.220.453.100.875
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| Concept/Terms |
Cytochrome P-450 CYP1B1- Cytochrome P-450 CYP1B1
- Cytochrome P 450 CYP1B1
- Cytochrome P450, Family 1, Subfamily B, Polypeptide 1
- Cytochrome P4501B1
- Cytochrome P450 CYP1B1
- P450 CYP1B1, Cytochrome
|
Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1B1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1B1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1B1" by people in this website by year, and whether "Cytochrome P-450 CYP1B1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 2 | 2 |
| 2024 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cytochrome P-450 CYP1B1" by people in Profiles.
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CYP1B1 knockout enhanced IFN-? production is required but not sufficient for protection of cigarette smoke-exposed mice against lethal influenza virus infection. Front Immunol. 2025; 16:1600025.
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Meta-analysis identifies key genes and pathways implicated in Benzo[a]pyrene exposure response. Chemosphere. 2024 Sep; 364:143121.
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CYP1B1, MYOC, and LTBP2 mutations in primary congenital glaucoma patients in the United States. Am J Ophthalmol. 2013 Mar; 155(3):508-517.e5.
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No association of genetic polymorphisms in CYP1B1 with primary open-angle glaucoma: a meta- and gene-based analysis. Mol Vis. 2012; 18:786-96.
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Genetic variants contributing to daunorubicin-induced cytotoxicity. Cancer Res. 2008 May 01; 68(9):3161-8.