Aryl Hydrocarbon Hydroxylases
"Aryl Hydrocarbon Hydroxylases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.
| Descriptor ID |
D001189
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| MeSH Number(s) |
D08.244.453.005 D08.811.682.690.708.170.010 D12.776.422.220.453.010
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Aryl Hydrocarbon Hydroxylases".
Below are MeSH descriptors whose meaning is more specific than "Aryl Hydrocarbon Hydroxylases".
This graph shows the total number of publications written about "Aryl Hydrocarbon Hydroxylases" by people in this website by year, and whether "Aryl Hydrocarbon Hydroxylases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Aryl Hydrocarbon Hydroxylases" by people in Profiles.
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Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARa-FGF21 axis. Toxicology. 2017 03 15; 379:12-21.
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An allele-specific PCR system for rapid detection and discrimination of the CYP2C19*4A, *4B, and *17 alleles: implications for clopidogrel response testing. J Mol Diagn. 2013 Nov; 15(6):783-9.
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Nicotine enhances ethanol-induced fat accumulation and collagen deposition but not inflammation in mouse liver. Alcohol. 2013 Aug; 47(5):353-7.
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CYP1B1, MYOC, and LTBP2 mutations in primary congenital glaucoma patients in the United States. Am J Ophthalmol. 2013 Mar; 155(3):508-517.e5.
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No association of genetic polymorphisms in CYP1B1 with primary open-angle glaucoma: a meta- and gene-based analysis. Mol Vis. 2012; 18:786-96.
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Warfarin-antiretroviral interactions. Ann Pharmacother. 2009 Feb; 43(2):322-8.
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Genetic variants contributing to daunorubicin-induced cytotoxicity. Cancer Res. 2008 May 01; 68(9):3161-8.
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Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. J Pharmacol Exp Ther. 2004 Aug; 310(2):528-35.
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Developmental regulation of the 3-methylcholanthrene- and dioxin-inducible CYP1A5 gene in chick embryo liver in vivo. Toxicol Appl Pharmacol. 1998 Jul; 151(1):166-73.
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Activities of benzphetamine N-demethylase and aryl hydrocarbon hydroxylase in cells isolated from gamma-glutamyl transpeptidase-positive foci and surrounding liver. J Natl Cancer Inst. 1985 Dec; 75(6):1107-12.