High-Throughput Nucleotide Sequencing

"High-Throughput Nucleotide Sequencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.

Descriptor ID	D059014
MeSH Number(s)	E05.393.760.319
Concept/Terms	High-Throughput Nucleotide Sequencing High-Throughput Nucleotide Sequencing High Throughput Nucleotide Sequencing Nucleotide Sequencing, High-Throughput Sequencing, High-Throughput Nucleotide Massively-Parallel Sequencing Massively-Parallel Sequencing Massively Parallel Sequencing Sequencing, Massively-Parallel Sequencings, Massively-Parallel High-Throughput RNA Sequencing High-Throughput RNA Sequencing High Throughput RNA Sequencing RNA Sequencing, High-Throughput Sequencing, High-Throughput RNA Deep Sequencing Deep Sequencing Deep Sequencings Sequencing, Deep Sequencings, Deep High-Throughput DNA Sequencing High-Throughput DNA Sequencing DNA Sequencing, High-Throughput High Throughput DNA Sequencing High-Throughput DNA Sequencings Sequencing, High-Throughput DNA

Below are MeSH descriptors whose meaning is more general than "High-Throughput Nucleotide Sequencing".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Sequence Analysis [E05.393.760]
High-Throughput Nucleotide Sequencing [E05.393.760.319]

Below are MeSH descriptors whose meaning is related to "High-Throughput Nucleotide Sequencing".

Below are MeSH descriptors whose meaning is more specific than "High-Throughput Nucleotide Sequencing".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "High-Throughput Nucleotide Sequencing" by people in this website by year, and whether "High-Throughput Nucleotide Sequencing" was a major or minor topic of these publications.

Bar chart showing 89 publications over 10 distinct years, with a maximum of 21 publications in 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2011	0	2	2
2013	0	3	3
2014	4	9	13
2015	5	16	21
2016	1	9	10
2017	1	6	7
2018	7	7	14
2019	5	9	14
2020	2	2	4
2021	0	1	1

Below are the most recent publications written about "High-Throughput Nucleotide Sequencing" by people in Profiles.

Rodin RE, Dou Y, Kwon M, Sherman MA, D'Gama AM, Doan RN, Rento LM, Girskis KM, Bohrson CL, Kim SN, Nadig A, Luquette LJ, Gulhan DC, Park PJ, Walsh CA. The landscape of somatic mutation in cerebral cortex of autistic and neurotypical individuals revealed by ultra-deep whole-genome sequencing. Nat Neurosci. 2021 02; 24(2):176-185.

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Filkins LM, Bryson AL, Miller SA, Mitchell SL. Navigating Clinical Utilization of Direct-from-Specimen Metagenomic Pathogen Detection: Clinical Applications, Limitations, and Testing Recommendations. Clin Chem. 2020 11 01; 66(11):1381-1395.

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Saul M, Poorman K, Tae H, Vanderwalde A, Stafford P, Spetzler D, Korn WM, Gatalica Z, Swensen J. Population bias in somatic measurement of microsatellite instability status. Cancer Med. 2020 09; 9(17):6452-6460.

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Zampaglione E, Kinde B, Place EM, Navarro-Gomez D, Maher M, Jamshidi F, Nassiri S, Mazzone JA, Finn C, Schlegel D, Comander J, Pierce EA, Bujakowska KM. Copy-number variation contributes 9% of pathogenicity in the inherited retinal degenerations. Genet Med. 2020 06; 22(6):1079-1087.

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Losic B, Craig AJ, Villacorta-Martin C, Martins-Filho SN, Akers N, Chen X, Ahsen ME, von Felden J, Labgaa I, D'Avola D, Allette K, Lira SA, Furtado GC, Garcia-Lezana T, Restrepo P, Stueck A, Ward SC, Fiel MI, Hiotis SP, Gunasekaran G, Sia D, Schadt EE, Sebra R, Schwartz M, Llovet JM, Thung S, Stolovitzky G, Villanueva A. Intratumoral heterogeneity and clonal evolution in liver cancer. Nat Commun. 2020 01 15; 11(1):291.

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Tanno H, Gould TM, McDaniel JR, Cao W, Tanno Y, Durrett RE, Park D, Cate SJ, Hildebrand WH, Dekker CL, Tian L, Weyand CM, Georgiou G, Goronzy JJ. Determinants governing T cell receptor a/ß-chain pairing in repertoire formation of identical twins. Proc Natl Acad Sci U S A. 2020 01 07; 117(1):532-540.

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Tripathi A, Grivas P. The utility of next generation sequencing in advanced urothelial carcinoma. Eur Urol Focus. 2020 01 15; 6(1):41-44.

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Govil T, Sharma W, Chauhan NK, Kumar S, Salem DR, Sani RK. "MINES" method for genomic DNA extraction from deep biosphere biofilms. J Microbiol Methods. 2019 12; 167:105730.

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Gargano SM, Senarathne W, Feldman R, Florento E, Stafford P, Swensen J, Vranic S, Gatalica Z. Novel therapeutic targets in salivary duct carcinoma uncovered by comprehensive molecular profiling. Cancer Med. 2019 12; 8(17):7322-7329.

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Wagner S, Roberson D, Boland J, Kreimer AR, Yeager M, Cullen M, Mirabello L, Dunn ST, Walker J, Zuna R, Porras C, Cortes B, Sampson J, Herrero R, Rodriguez AC, Quint W, Van Doorn LJ, Hildesheim A, Schiffman M, Wentzensen N. Evaluation of TypeSeq, a Novel High-Throughput, Low-Cost, Next-Generation Sequencing-Based Assay for Detection of 51 Human Papillomavirus Genotypes. J Infect Dis. 2019 10 08; 220(10):1609-1619.

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