Receptors, Leukocyte-Adhesion
"Receptors, Leukocyte-Adhesion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Family of proteins associated with the capacity of LEUKOCYTES to adhere to each other and to certain substrata, e.g., the C3bi component of complement. Members of this family are the LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; (LFA-1), the MACROPHAGE-1 ANTIGEN; (Mac-1), and the INTEGRIN ALPHAXBETA2 or p150,95 leukocyte adhesion protein. They all share a common beta-subunit which is the CD18 antigen. All three of the above antigens are absent in inherited LEUKOCYTE-ADHESION DEFICIENCY SYNDROME, which is characterized by recurrent bacterial infections, impaired pus formation, and wound healing as well as abnormalities in a wide spectrum of adherence-dependent functions of granulocytes, monocytes, and lymphoid cells.
| Descriptor ID |
D016028
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| MeSH Number(s) |
D12.776.543.750.705.408.600
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| Concept/Terms |
Receptors, Leukocyte-Adhesion- Receptors, Leukocyte-Adhesion
- Receptors, Leukocyte Adhesion
- Leukocyte-Adhesion Receptor
- Leukocyte Adhesion Receptor
- Receptor, Leukocyte-Adhesion
- Leukocyte-Adhesion Receptor Family
- Leukocyte Adhesion Receptor Family
- Leu-CAM Receptor Family
- Family, Leu-CAM Receptor
- Leu CAM Receptor Family
- Receptor Family, Leu-CAM
- Leukocyte-Adhesion Receptors
- Leukocyte Adhesion Receptors
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Below are MeSH descriptors whose meaning is more general than "Receptors, Leukocyte-Adhesion".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Leukocyte-Adhesion".
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Below are the most recent publications written about "Receptors, Leukocyte-Adhesion" by people in Profiles.
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Staurosporine inhibits neutrophil phagocytosis but not iC3b binding mediated by CR3 (CD11b/CD18). J Immunol. 1991 May 15; 146(10):3557-62.
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Two pathways of CD11b/CD18-mediated neutrophil aggregation with different involvement of protein kinase C-dependent phosphorylation. J Immunol. 1990 Oct 15; 145(8):2608-15.