"Integrin beta Chains" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Integrin beta chains combine with integrin alpha chains to form heterodimeric cell surface receptors. Integrins have traditionally been classified into functional groups based on the identity of one of three beta chains present in the heterodimer. The beta chain is necessary and sufficient for integrin-dependent signaling. Its short cytoplasmic tail contains sequences critical for inside-out signaling.
| Descriptor ID |
D039641
|
| MeSH Number(s) |
D12.776.543.750.705.408.200
|
| Concept/Terms |
Integrin beta Chains- Integrin beta Chains
- beta Chains, Integrin
- Integrin beta Subunits
- beta Integrins
- Integrins, beta
|
Below are MeSH descriptors whose meaning is more general than "Integrin beta Chains".
Below are MeSH descriptors whose meaning is more specific than "Integrin beta Chains".
This graph shows the total number of publications written about "Integrin beta Chains" by people in this website by year, and whether "Integrin beta Chains" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
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Below are the most recent publications written about "Integrin beta Chains" by people in Profiles.
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Mice lacking the integrin beta5 subunit have accelerated osteoclast maturation and increased activity in the estrogen-deficient state. J Bone Miner Res. 2005 Jan; 20(1):58-66.
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Specific inhibition of T lymphocyte coactivation by triggering integrin beta 1 reveals convergence of beta 1, beta 2, and beta 7 signaling pathways. J Immunol. 1996 Jul 15; 157(2):700-6.