"Telomere Shortening" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.
| Descriptor ID |
D059506
|
| MeSH Number(s) |
G02.111.225.940 G04.043.630 G05.226.940
|
| Concept/Terms |
Telomere Shortening- Telomere Shortening
- Shortening, Telomere
- Shortenings, Telomere
- Telomere Shortenings
|
Below are MeSH descriptors whose meaning is more general than "Telomere Shortening".
Below are MeSH descriptors whose meaning is more specific than "Telomere Shortening".
This graph shows the total number of publications written about "Telomere Shortening" by people in this website by year, and whether "Telomere Shortening" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
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Below are the most recent publications written about "Telomere Shortening" by people in Profiles.
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Pharmacodynamics of telomerase inhibition and telomere shortening by noncytotoxic suramin. AAPS J. 2015 Jan; 17(1):268-76.
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Smoking accelerates aging of the small airway epithelium. Respir Res. 2014 Sep 24; 15:94.
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Novel neuroendocrine and metabolic mechanism provides the patented platform for important rejuvenation therapies: targeted therapy of telomere attrition and lifestyle changes of telomerase activity with the timing of neuron-specific imidazole-containing dipeptide-dominant pharmaconutrition provision. Recent Pat Endocr Metab Immune Drug Discov. 2014; 8(3):153-79.
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Short leukocyte telomere length predicts risk of diabetes in american indians: the strong heart family study. Diabetes. 2014 Jan; 63(1):354-62.