"Cellular Senescence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing CELL DEATH. Senescence can be induced by DNA DAMAGE or other cellular stresses, such as OXIDATIVE STRESS.
| Descriptor ID |
D016922
|
| MeSH Number(s) |
G04.043
|
| Concept/Terms |
Cell Aging- Cell Aging
- Cellular Ageing
- Ageing, Cellular
- Aging, Cell
- Senescence, Replicative
- Cellular Aging
- Aging, Cellular
- Replicative Senescence
- Cell Ageing
- Ageing, Cell
Senescence-Associated Secretory Phenotype- Senescence-Associated Secretory Phenotype
- Phenotype, Senescence-Associated Secretory
- Secretory Phenotype, Senescence-Associated
- Senescence Associated Secretory Phenotype
|
Below are MeSH descriptors whose meaning is more general than "Cellular Senescence".
Below are MeSH descriptors whose meaning is more specific than "Cellular Senescence".
This graph shows the total number of publications written about "Cellular Senescence" by people in this website by year, and whether "Cellular Senescence" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2008 | 1 | 2 | 3 |
| 2009 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 4 | 1 | 5 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 2 | 4 |
| 2015 | 3 | 0 | 3 |
| 2016 | 2 | 2 | 4 |
| 2017 | 0 | 2 | 2 |
| 2018 | 3 | 1 | 4 |
| 2019 | 2 | 3 | 5 |
| 2020 | 3 | 2 | 5 |
| 2021 | 2 | 1 | 3 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 1 | 1 |
| 2024 | 2 | 1 | 3 |
| 2025 | 1 | 1 | 2 |
| 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cellular Senescence" by people in Profiles.
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Lipid-laden endothelial cells exhibit a transcriptomic signature linked to blood-brain barrier dysfunction, metabolic reprogramming, and increased inflammation in the aging brain. Geroscience. 2026 Apr; 48(2):1735-1750.
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Peroxisome Proliferator-Activated Receptor a Deficiency Induces Vascular Pathologies through Endothelial Senescence in Diabetic Retinopathy. Am J Pathol. 2026 Apr; 196(4):960-975.
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Necroptosis induced by MLKL overexpression in liver triggers cellular senescence and leads to chronic inflammation and fibrosis. Geroscience. 2026 Apr; 48(2):1917-1935.
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Irradiation-induced brain senescence accelerates cardiac aging via systemic mechanisms: insights from transcriptomic profiling. Geroscience. 2026 Feb; 48(1):951-971.
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RNA-binding protein AUF1 suppresses cellular senescence and glycolysis by targeting PDP2 and PGAM1 mRNAs. Aging (Albany NY). 2025 Jul 24; 17(7):1746-1761.
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Radiation Promotes Acute and Chronic Damage to Adipose Tissue. Int J Mol Sci. 2025 Jun 12; 26(12).
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Palmitic Acid Induces Oxidative Stress and Senescence in Human Brainstem Astrocytes, Downregulating Glutamate Reuptake Transporters-Implications for Obesity-Related Sympathoexcitation. Nutrients. 2024 Aug 26; 16(17).
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MASLD does not affect fertility and senolytics fail to prevent MASLD progression in male mice. Sci Rep. 2024 07 27; 14(1):17332.
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Reproductive Ageing: Inflammation, immune cells, and cellular senescence in the aging ovary. Reproduction. 2024 Aug 01; 168(2).
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Accelerated Aging Induced by an Unhealthy High-Fat Diet: Initial Evidence for the Role of Nrf2 Deficiency and Impaired Stress Resilience in Cellular Senescence. Nutrients. 2024 Mar 26; 16(7).