Interleukin-8

"Interleukin-8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A member of the CXC chemokine family that plays a role in the regulation of the acute inflammatory response. It is secreted by variety of cell types and induces CHEMOTAXIS of NEUTROPHILS and other inflammatory cells.

Descriptor ID	D016209
MeSH Number(s)	D12.644.276.374.200.120.800 D12.644.276.374.465.312 D12.776.467.374.200.120.800 D12.776.467.374.465.246 D23.125.300.120.800 D23.469.200.120.800 D23.529.374.200.120.800 D23.529.374.465.312
Concept/Terms	Interleukin-8 Interleukin-8 Interleukin 8 IL8 Monocyte-Derived Neutrophil Chemotactic Factor Neutrophil Activation Factor Neutrophil-Activating Peptide, Lymphocyte-Derived Lymphocyte-Derived Neutrophil-Activating Peptide Neutrophil Activating Peptide, Lymphocyte Derived Neutrophil-Activating Peptide, Monocyte-Derived Monocyte-Derived Neutrophil-Activating Peptide Neutrophil Activating Peptide, Monocyte Derived Alveolar Macrophage Chemotactic Factor-I Alveolar Macrophage Chemotactic Factor I AMCF-I Anionic Neutrophil-Activating Peptide Anionic Neutrophil Activating Peptide Neutrophil-Activating Peptide, Anionic Peptide, Anionic Neutrophil-Activating Chemokine CXCL8 CXCL8, Chemokine Chemokines, CXCL8 CXCL8 Chemokines Chemotactic Factor, Macrophage-Derived Chemotactic Factor, Macrophage Derived Macrophage-Derived Chemotactic Factor Chemotactic Factor, Neutrophil Neutrophil Chemotactic Factor Chemotactic Factor, Neutrophil, Monocyte-Derived CXCL8 Chemokine Chemokine, CXCL8 Granulocyte Chemotactic Peptide-Interleukin-8 Chemotactic Peptide-Interleukin-8, Granulocyte Granulocyte Chemotactic Peptide Interleukin 8 IL-8

Below are MeSH descriptors whose meaning is more general than "Interleukin-8".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Chemokines [D12.644.276.374.200]
Chemokines, CXC [D12.644.276.374.200.120]
Interleukin-8 [D12.644.276.374.200.120.800]
Interleukins [D12.644.276.374.465]
Interleukin-8 [D12.644.276.374.465.312]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Chemokines [D12.776.467.374.200]
Chemokines, CXC [D12.776.467.374.200.120]
Interleukin-8 [D12.776.467.374.200.120.800]
Interleukins [D12.776.467.374.465]
Interleukin-8 [D12.776.467.374.465.246]
Biological Factors [D23]
Chemotactic Factors [D23.125]
Chemokines [D23.125.300]
Chemokines, CXC [D23.125.300.120]
Interleukin-8 [D23.125.300.120.800]
Inflammation Mediators [D23.469]
Chemokines [D23.469.200]
Chemokines, CXC [D23.469.200.120]
Interleukin-8 [D23.469.200.120.800]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Chemokines [D23.529.374.200]
Chemokines, CXC [D23.529.374.200.120]
Interleukin-8 [D23.529.374.200.120.800]
Interleukins [D23.529.374.465]
Interleukin-8 [D23.529.374.465.312]

Below are MeSH descriptors whose meaning is more specific than "Interleukin-8".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-8" by people in this website by year, and whether "Interleukin-8" was a major or minor topic of these publications.

Bar chart showing 21 publications over 14 distinct years, with a maximum of 4 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	1	0	1
2000	2	0	2
2001	2	0	2
2003	0	1	1
2004	1	0	1
2006	1	0	1
2007	0	1	1
2008	2	2	4
2012	0	1	1
2013	0	3	3
2017	0	1	1
2018	0	1	1
2020	0	1	1

Below are the most recent publications written about "Interleukin-8" by people in Profiles.

Lam AK, Panlilio H, Pusavat J, Wouters CL, Moen EL, Brennan RE, Rice CV. Expanding the Spectrum of Antibiotics Capable of Killing Multidrug-Resistant Staphylococcus aureus and Pseudomonas aeruginosa. ChemMedChem. 2020 08 05; 15(15):1421-1428.

View in: PubMed
Booth JL, Duggan ES, Patel VI, Wu W, Burian DM, Hutchings DC, White VL, Coggeshall KM, Dozmorov MG, Metcalf JP. Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines. Microb Pathog. 2018 Aug; 121:9-21.

View in: PubMed
Bakker R, Pierce S, Myers D. The role of prostaglandins E1 and E2, dinoprostone, and misoprostol in cervical ripening and the induction of labor: a mechanistic approach. Arch Gynecol Obstet. 2017 Aug; 296(2):167-179.

View in: PubMed
Crow SS, Oliver WC, Kiefer JA, Snyder MR, Dearani JA, Li Z, Burkhart HM. Dexamethasone levels predict cortisol response after infant cardiopulmonary bypass. J Thorac Cardiovasc Surg. 2014 Jan; 147(1):475-81.

View in: PubMed
Gardner AW, Parker DE, Montgomery PS, Sosnowska D, Casanegra AI, Esponda OL, Ungvari Z, Csiszar A, Sonntag WE. Impaired vascular endothelial growth factor A and inflammation in patients with peripheral artery disease. Angiology. 2014 Sep; 65(8):683-90.

View in: PubMed
Gomez-Lopez N, Vega-Sanchez R, Castillo-Castrejon M, Romero R, Cubeiro-Arreola K, Vadillo-Ortega F. Evidence for a role for the adaptive immune response in human term parturition. Am J Reprod Immunol. 2013 Mar; 69(3):212-30.

View in: PubMed
Wu W, Zhang W, Booth JL, Metcalf JP. Influenza A(H1N1)pdm09 virus suppresses RIG-I initiated innate antiviral responses in the human lung. PLoS One. 2012; 7(11):e49856.

View in: PubMed
Sureban SM, Ramalingam S, Natarajan G, May R, Subramaniam D, Bishnupuri KS, Morrison AR, Dieckgraefe BK, Brackett DJ, Postier RG, Houchen CW, Anant S. Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe. Oncogene. 2008 Jul 31; 27(33):4544-56.

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Subramaniam D, May R, Sureban SM, Lee KB, George R, Kuppusamy P, Ramanujam RP, Hideg K, Dieckgraefe BK, Houchen CW, Anant S. Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity. Cancer Res. 2008 Mar 15; 68(6):1962-9.

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Rajaiya J, Xiao J, Rajala RV, Chodosh J. Human adenovirus type 19 infection of corneal cells induces p38 MAPK-dependent interleukin-8 expression. Virol J. 2008 Jan 25; 5:17.

View in: PubMed

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