"Interleukin-4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A soluble factor produced by activated T-LYMPHOCYTES that induces the expression of MHC CLASS II GENES and FC RECEPTORS on B-LYMPHOCYTES and causes their proliferation and differentiation. It also acts on T-lymphocytes, MAST CELLS, and several other hematopoietic lineage cells.
| Descriptor ID |
D015847
|
| MeSH Number(s) |
D12.644.276.374.465.186 D12.776.467.374.465.178 D23.529.374.465.186
|
| Concept/Terms |
Interleukin-4- Interleukin-4
- Interleukin 4
- B-Cell Growth Factor-1
- B Cell Growth Factor 1
- B-Cell Growth Factor-I
- B Cell Growth Factor I
- B-Cell Proliferating Factor
- B Cell Proliferating Factor
- B-Cell Stimulating Factor-1
- B Cell Stimulating Factor 1
- B-Cell Stimulatory Factor 1
- B-Cell Stimulatory Factor-1
- BCGF-1
- Binetrakin
- BSF-1
- IL-4
- IL4
- Mast Cell Growth Factor-2
- Mast Cell Growth Factor 2
- MCGF-2
- B Cell Stimulatory Factor-1
- B Cell Stimulatory Factor 1
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-4".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-4".
This graph shows the total number of publications written about "Interleukin-4" by people in this website by year, and whether "Interleukin-4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 2 | 3 |
| 2000 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 2 | 2 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "Interleukin-4" by people in Profiles.
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Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors. J Exp Med. 2019 04 01; 216(4):884-899.
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Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling. Int J Mol Sci. 2019 Mar 07; 20(5).
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Immunogenicity of a Staphylococcus aureus-cholera toxin A2/B vaccine for bovine mastitis. Vaccine. 2018 06 07; 36(24):3513-3521.
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Coordination between T helper cells, iNKT cells, and their follicular helper subsets in the humoral immune response against Clostridium difficile toxin B. J Leukoc Biol. 2017 02; 101(2):567-576.
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IL-4 promotes asymmetric dimethylarginine accumulation, oxo-nitrative stress, and hypoxic response-induced mitochondrial loss in airway epithelial cells. J Allergy Clin Immunol. 2016 07; 138(1):130-141.e9.
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Temporal neutrophil polarization following myocardial infarction. Cardiovasc Res. 2016 May 01; 110(1):51-61.
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Mast cells aggravate sepsis by inhibiting peritoneal macrophage phagocytosis. J Clin Invest. 2014 Oct; 124(10):4577-89.
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Use of an Sm-p80-based therapeutic vaccine to kill established adult schistosome parasites in chronically infected baboons. J Infect Dis. 2014 Jun 15; 209(12):1929-40.
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Regulation of anthrax toxin-specific antibody titers by natural killer T cell-derived IL-4 and IFN?. PLoS One. 2011; 6(8):e23817.
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Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system. Cell. 2008 Jan 25; 132(2):259-72.