"Casein Kinase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous casein kinase that is comprised of two distinct catalytic subunits and dimeric regulatory subunit. Casein kinase II has been shown to phosphorylate a large number of substrates, many of which are proteins involved in the regulation of gene expression.
| Descriptor ID |
D047390
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.140.600 D12.776.476.150.600
|
| Concept/Terms |
Casein Kinase II- Casein Kinase II
- Protein Kinase CKII
- Kinase CKII, Protein
- Casein Kinase-2
- Protein Kinase CK2
- Casein Kinase 2
- Casein Kinase TS
|
Below are MeSH descriptors whose meaning is more general than "Casein Kinase II".
Below are MeSH descriptors whose meaning is more specific than "Casein Kinase II".
This graph shows the total number of publications written about "Casein Kinase II" by people in this website by year, and whether "Casein Kinase II" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Casein Kinase II" by people in Profiles.
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BMI1, a new target of CK2a. Mol Cancer. 2017 03 07; 16(1):56.
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Identification of a New Susceptibility Locus for Systemic Lupus Erythematosus on Chromosome 12 in Individuals of European Ancestry. Arthritis Rheumatol. 2016 Jan; 68(1):174-83.
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Genome-wide association study identifies variants in casein kinase II (CSNK2A2) to be associated with leukocyte telomere length in a Punjabi Sikh diabetic cohort. Circ Cardiovasc Genet. 2014 Jun; 7(3):287-95.
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CD5-dependent CK2 activation pathway regulates threshold for T cell anergy. J Immunol. 2012 Sep 15; 189(6):2918-30.
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A rice kinase-protein interaction map. Plant Physiol. 2009 Mar; 149(3):1478-92.
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CD5-CK2 binding/activation-deficient mice are resistant to experimental autoimmune encephalomyelitis: protection is associated with diminished populations of IL-17-expressing T cells in the central nervous system. J Immunol. 2006 Dec 15; 177(12):8542-9.
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Breaking in a new function for casein kinase 2. Sci Aging Knowledge Environ. 2004 Jun 02; 2004(22):pe24.
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Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis. J Biol Chem. 2002 Jul 05; 277(27):24232-42.
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Interactions between protein kinase CK2 and Pin1. Evidence for phosphorylation-dependent interactions. J Biol Chem. 2002 Jun 21; 277(25):23054-64.
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Casein kinase II catalyzes a mitotic phosphorylation on threonine 1342 of human DNA topoisomerase IIalpha, which is recognized by the 3F3/2 phosphoepitope antibody. J Biol Chem. 1998 Nov 13; 273(46):30622-9.