Immediate-Early Proteins

"Immediate-Early Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.

Descriptor ID	D017874
MeSH Number(s)	D12.776.460 D12.776.964.925.968
Concept/Terms	Immediate-Early Proteins Immediate-Early Proteins Immediate Early Proteins Proteins, Immediate-Early Proteins, Immediate Early

Below are MeSH descriptors whose meaning is more general than "Immediate-Early Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Immediate-Early Proteins [D12.776.460]
Viral Proteins [D12.776.964]
Viral Regulatory and Accessory Proteins [D12.776.964.925]
Immediate-Early Proteins [D12.776.964.925.968]

Below are MeSH descriptors whose meaning is related to "Immediate-Early Proteins".

Below are MeSH descriptors whose meaning is more specific than "Immediate-Early Proteins".

Immediate-Early Proteins
Adenovirus E1 Proteins
Butyrate Response Factor 1
Early Growth Response Transcription Factors
Tristetraprolin

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immediate-Early Proteins" by people in this website by year, and whether "Immediate-Early Proteins" was a major or minor topic of these publications.

Bar chart showing 18 publications over 11 distinct years, with a maximum of 3 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	0	1
2002	1	0	1
2003	2	0	2
2004	2	0	2
2005	2	0	2
2006	1	2	3
2007	1	0	1
2008	1	1	2
2009	1	0	1
2010	1	1	2
2011	1	0	1

Below are the most recent publications written about "Immediate-Early Proteins" by people in Profiles.

Wuest T, Zheng M, Efstathiou S, Halford WP, Carr DJ. The herpes simplex virus-1 transactivator infected cell protein-4 drives VEGF-A dependent neovascularization. PLoS Pathog. 2011 Oct; 7(10):e1002278.

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Walters MS, Kyratsous CA, Silverstein SJ. The RING finger domain of Varicella-Zoster virus ORF61p has E3 ubiquitin ligase activity that is essential for efficient autoubiquitination and dispersion of Sp100-containing nuclear bodies. J Virol. 2010 Jul; 84(13):6861-5.

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Mueller NH, Walters MS, Marcus RA, Graf LL, Prenni J, Gilden D, Silverstein SJ, Cohrs RJ. Identification of phosphorylated residues on varicella-zoster virus immediate-early protein ORF63. J Gen Virol. 2010 May; 91(Pt 5):1133-7.

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Kyratsous CA, Walters MS, Panagiotidis CA, Silverstein SJ. Complementation of a herpes simplex virus ICP0 null mutant by varicella-zoster virus ORF61p. J Virol. 2009 Oct; 83(20):10637-43.

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Poole BD, Gross T, Maier S, Harley JB, James JA. Lupus-like autoantibody development in rabbits and mice after immunization with EBNA-1 fragments. J Autoimmun. 2008 Dec; 31(4):362-71.

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Walters MS, Kyratsous CA, Wan S, Silverstein S. Nuclear import of the varicella-zoster virus latency-associated protein ORF63 in primary neurons requires expression of the lytic protein ORF61 and occurs in a proteasome-dependent manner. J Virol. 2008 Sep; 82(17):8673-86.

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Staudt MR, Dittmer DP. The Rta/Orf50 transactivator proteins of the gamma-herpesviridae. Curr Top Microbiol Immunol. 2007; 312:71-100.

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Halford WP, Weisend C, Grace J, Soboleski M, Carr DJ, Balliet JW, Imai Y, Margolis TP, Gebhardt BM. ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency. Virol J. 2006 Jun 09; 3:44.

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Wang JJ, Zhang SX, Mott R, Knapp RR, Cao W, Lau K, Ma JX. Salutary effect of pigment epithelium-derived factor in diabetic nephropathy: evidence for antifibrogenic activities. Diabetes. 2006 Jun; 55(6):1678-85.

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Staudt MR, Dittmer DP. Promoter switching allows simultaneous transcription of LANA and K14/vGPCR of Kaposi's sarcoma-associated herpesvirus. Virology. 2006 Jun 20; 350(1):192-205.

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