CRISPR-Associated Proteins
"CRISPR-Associated Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein components of the CRISPR-CAS SYSTEMS for anti-viral defense in ARCHAEA and BACTERIA. These are proteins that carry out a variety of functions during the creation and expansion of the CRISPR ARRAYS, the capture of new CRISPR SPACERS, biogenesis of SMALL INTERFERING RNA (CRISPR or crRNAs), and the targeting and silencing of invading viruses and plasmids. They include DNA HELICASES; RNA-BINDING PROTEINS; ENDONUCLEASES; and RNA and DNA POLYMERASES.
| Descriptor ID |
D064130
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| MeSH Number(s) |
D12.776.212
|
| Concept/Terms |
CRISPR-Associated Protein Complex Proteins- CRISPR-Associated Protein Complex Proteins
- CRISPR Associated Protein Complex Proteins
- CRISPR-Associated Complex for Antiviral Defense Proteins
- CRISPR Associated Complex for Antiviral Defense Proteins
- CASCADE Proteins, CRISPR-Associated
- CASCADE Proteins, CRISPR Associated
- CRISPR-Associated CASCADE Proteins
|
Below are MeSH descriptors whose meaning is more general than "CRISPR-Associated Proteins".
Below are MeSH descriptors whose meaning is more specific than "CRISPR-Associated Proteins".
This graph shows the total number of publications written about "CRISPR-Associated Proteins" by people in this website by year, and whether "CRISPR-Associated Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "CRISPR-Associated Proteins" by people in Profiles.
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In Situ Complexation of sgRNA and Cas12a Improves the Performance of a One-Pot RPA-CRISPR-Cas12 Assay. Anal Chem. 2024 06 25; 96(25):10443-10450.
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Unity among the diverse RNA-guided CRISPR-Cas interference mechanisms. J Biol Chem. 2024 Jun; 300(6):107295.
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The bridge helix of Cas12a imparts selectivity in cis-DNA cleavage and regulates trans-DNA cleavage. FEBS Lett. 2021 04; 595(7):892-912.
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CRISPR type II-A subgroups exhibit phylogenetically distinct mechanisms for prespacer insertion. J Biol Chem. 2020 08 07; 295(32):10956-10968.
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DNA Origami Post-Processing by CRISPR-Cas12a. Angew Chem Int Ed Engl. 2020 03 02; 59(10):3956-3960.
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RNA-Independent DNA Cleavage Activities of Cas9 and Cas12a. Cell Rep. 2017 12 26; 21(13):3728-3739.