Clustered Regularly Interspaced Short Palindromic Repeats
"Clustered Regularly Interspaced Short Palindromic Repeats" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Repetitive nucleic acid sequences that are principal components of the archaeal and bacterial CRISPR-CAS SYSTEMS, which function as adaptive antiviral defense systems.
| Descriptor ID |
D064112
|
| MeSH Number(s) |
G02.111.570.080.708.800.325.500 G05.360.080.708.800.325.500 G05.360.340.024.850.069
|
| Concept/Terms |
Clustered Regularly Interspaced Short Palindromic Repeats- Clustered Regularly Interspaced Short Palindromic Repeats
- CRISPRs
- CRISPR
- CRISPR Sequences
- CRISPR Sequence
- Sequence, CRISPR
- Sequences, CRISPR
- Clustered Regularly Interspaced Short Palindromic Repeat
- CRISPR Elements
- CRISPR Element
- Element, CRISPR
- Elements, CRISPR
CRISPR Spacers- CRISPR Spacers
- CRISPR Spacer
- Spacer, CRISPR
- Spacers, CRISPR
- CRISPR Spacer Sequences
- CRISPR Spacer Sequence
- Sequence, CRISPR Spacer
- Sequences, CRISPR Spacer
- Spacer Sequence, CRISPR
- Spacer Sequences, CRISPR
CRISPR-Cas Loci- CRISPR-Cas Loci
- CRISPR Cas Loci
- CRISPR-Cas Locus
- Loci, CRISPR-Cas
- Locus, CRISPR-Cas
CRISPR Loci- CRISPR Loci
- Loci, CRISPR
- Locus, CRISPR
- CRISPR Clusters
- CRISPR Cluster
- Cluster, CRISPR
- Clusters, CRISPR
- CRISPR Locus
- CRISPR Arrays
- Array, CRISPR
- Arrays, CRISPR
- CRISPR Array
|
Below are MeSH descriptors whose meaning is more general than "Clustered Regularly Interspaced Short Palindromic Repeats".
Below are MeSH descriptors whose meaning is more specific than "Clustered Regularly Interspaced Short Palindromic Repeats".
This graph shows the total number of publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in this website by year, and whether "Clustered Regularly Interspaced Short Palindromic Repeats" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 2 | 0 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clustered Regularly Interspaced Short Palindromic Repeats" by people in Profiles.
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Unity among the diverse RNA-guided CRISPR-Cas interference mechanisms. J Biol Chem. 2024 Jun; 300(6):107295.
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Coordinated Actions of Cas9 HNH and RuvC Nuclease Domains Are Regulated by the Bridge Helix and the Target DNA Sequence. Biochemistry. 2021 12 14; 60(49):3783-3800.
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The CRISPR-Cas Mechanism for Adaptive Immunity and Alternate Bacterial Functions Fuels Diverse Biotechnologies. Front Cell Infect Microbiol. 2020; 10:619763.
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Identification of a Distal Locus Enhancer Element That Controls Cell Type-Specific TNF and LTA Gene Expression in Human T Cells. J Immunol. 2020 11 01; 205(9):2479-2488.
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DNA Origami Post-Processing by CRISPR-Cas12a. Angew Chem Int Ed Engl. 2020 03 02; 59(10):3956-3960.
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Functional genomics of the rapidly replicating bacterium Vibrio natriegens by CRISPRi. Nat Microbiol. 2019 07; 4(7):1105-1113.
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Switchable genome editing via genetic code expansion. Sci Rep. 2018 07 03; 8(1):10051.
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The Revolution Continues: Newly Discovered Systems Expand the CRISPR-Cas Toolkit. Mol Cell. 2017 Oct 05; 68(1):15-25.
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Ethical issues of CRISPR technology and gene editing through the lens of solidarity. Br Med Bull. 2017 06 01; 122(1):17-29.
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PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression. Gene. 2017 May 15; 612:55-60.