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Suppressor of Cytokine Signaling 1 Protein

"Suppressor of Cytokine Signaling 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A suppressor of cytokine signaling protein that consists of an N-terminal kinase-inhibitory region, a central SH2 DOMAIN, a characteristic C-terminal SOCS box (a 40-amino acid motif, which functions to recruit E3 UBIQUITIN-PROTEIN LIGASE COMPLEXES). SOCS1 functions as a negative regulator of CYTOKINES that signal through the JANUS KINASES-STAT 3 TRANSCRIPTION FACTOR (JAK/STAT3) pathway by inhibiting the activity of JANUS KINASES.


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This graph shows the total number of publications written about "Suppressor of Cytokine Signaling 1 Protein" by people in this website by year, and whether "Suppressor of Cytokine Signaling 1 Protein" was a major or minor topic of these publications.
Bar chart showing 2 publications over 1 distinct years, with a maximum of 2 publications in 2004
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