"Kynurenic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A broad-spectrum excitatory amino acid antagonist used as a research tool.
| Descriptor ID |
D007736
|
| MeSH Number(s) |
D03.066.942.505 D03.633.100.810.350.400
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Kynurenic Acid".
Below are MeSH descriptors whose meaning is more specific than "Kynurenic Acid".
This graph shows the total number of publications written about "Kynurenic Acid" by people in this website by year, and whether "Kynurenic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 2 | 0 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 0 | 3 |
| 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Kynurenic Acid" by people in Profiles.
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Acute administration of ibuprofen increases serum concentration of the neuroprotective kynurenine pathway metabolite, kynurenic acid: a pilot randomized, placebo-controlled, crossover study. Psychopharmacology (Berl). 2022 Dec; 239(12):3919-3927.
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C-Reactive protein and the kynurenic acid to quinolinic acid ratio are independently associated with white matter integrity in major depressive disorder. Brain Behav Immun. 2022 10; 105:180-189.
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Kynurenic acid is reduced in females and oral contraceptive users: Implications for depression. Brain Behav Immun. 2018 Jan; 67:59-64.
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Sleep disturbance and kynurenine metabolism in depression. J Psychosom Res. 2017 08; 99:1-7.
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Serum kynurenic acid is reduced in affective psychosis. Transl Psychiatry. 2017 05 02; 7(5):e1115.
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Kynurenine pathway metabolites are associated with hippocampal activity during autobiographical memory recall in patients with depression. Brain Behav Immun. 2016 Aug; 56:335-42.
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Relationship between neurotoxic kynurenine metabolites and reductions in right medial prefrontal cortical thickness in major depressive disorder. Brain Behav Immun. 2016 Mar; 53:39-48.
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Activation of the kynurenine pathway is associated with striatal volume in major depressive disorder. Psychoneuroendocrinology. 2015 Dec; 62:54-8.
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Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder. Brain Behav Immun. 2015 May; 46:55-9.
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Neuroprotective kynurenine metabolite indices are abnormally reduced and positively associated with hippocampal and amygdalar volume in bipolar disorder. Psychoneuroendocrinology. 2015 Feb; 52:200-11.