Vascular Endothelial Growth Factor A
"Vascular Endothelial Growth Factor A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The original member of the family of endothelial cell growth factors referred to as VASCULAR ENDOTHELIAL GROWTH FACTORS. Vascular endothelial growth factor-A was originally isolated from tumor cells and referred to as "tumor angiogenesis factor" and "vascular permeability factor". Although expressed at high levels in certain tumor-derived cells it is produced by a wide variety of cell types. In addition to stimulating vascular growth and vascular permeability it may play a role in stimulating VASODILATION via NITRIC OXIDE-dependent pathways. Alternative splicing of the mRNA for vascular endothelial growth factor A results in several isoforms of the protein being produced.
| Descriptor ID |
D042461
|
| MeSH Number(s) |
D12.644.276.100.800.200 D12.776.467.100.800.200 D23.529.100.800.200
|
| Concept/Terms |
Vascular Endothelial Growth Factor A- Vascular Endothelial Growth Factor A
- Vascular Endothelial Growth Factor-A
- VEGF-A
- Vasculotropin
- VEGF
- Vascular Endothelial Growth Factor
- Vascular Permeability Factor
- Permeability Factor, Vascular
|
Below are MeSH descriptors whose meaning is more general than "Vascular Endothelial Growth Factor A".
Below are MeSH descriptors whose meaning is more specific than "Vascular Endothelial Growth Factor A".
This graph shows the total number of publications written about "Vascular Endothelial Growth Factor A" by people in this website by year, and whether "Vascular Endothelial Growth Factor A" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 1 | 2 |
| 2005 | 3 | 3 | 6 |
| 2006 | 1 | 3 | 4 |
| 2007 | 0 | 6 | 6 |
| 2008 | 0 | 4 | 4 |
| 2009 | 8 | 4 | 12 |
| 2010 | 5 | 6 | 11 |
| 2011 | 3 | 3 | 6 |
| 2012 | 4 | 6 | 10 |
| 2013 | 2 | 6 | 8 |
| 2014 | 2 | 4 | 6 |
| 2015 | 2 | 4 | 6 |
| 2016 | 1 | 3 | 4 |
| 2017 | 3 | 5 | 8 |
| 2018 | 3 | 0 | 3 |
| 2019 | 3 | 2 | 5 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Vascular Endothelial Growth Factor A" by people in Profiles.
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McFaline-Figueroa JR, Kaley TJ, Dunn IF, Bi WL. Biology and Treatment of Meningiomas: A Reappraisal. Hematol Oncol Clin North Am. 2022 02; 36(1):133-146.
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Xu M, Jiang Y, Su L, Chen X, Shao X, Ea V, Shang Z, Zhang X, Barnstable CJ, Li X, Tombran-Tink J. Novel Regulators of Retina Neovascularization: A Proteomics Approach. J Proteome Res. 2022 01 07; 21(1):101-117.
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Hartono SP, Bedell VM, Alam SK, O'Gorman M, Serres M, Hall SR, Pal K, Kudgus RA, Mukherjee P, Seelig DM, Meves A, Mukhopadhyay D, Ekker SC, Hoeppner LH. Vascular Endothelial Growth Factor as an Immediate-Early Activator of Ultraviolet-Induced Skin Injury. Mayo Clin Proc. 2022 01; 97(1):154-164.
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Hu J, Zhu M, Li D, Wu Q, Le YZ. VEGF as a Direct Functional Regulator of Photoreceptors and Contributing Factor to Diabetes-Induced Alteration of Photoreceptor Function. Biomolecules. 2021 07 05; 11(7).
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Le YZ, Xu B, Chucair-Elliott AJ, Zhang H, Zhu M. VEGF Mediates Retinal Müller Cell Viability and Neuroprotection through BDNF in Diabetes. Biomolecules. 2021 05 10; 11(5).
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Saxena A, Walters MS, Shieh JH, Shen LB, Gomi K, Downey RJ, Crystal RG, Moore MAS. Extracellular vesicles from human airway basal cells respond to cigarette smoke extract and affect vascular endothelial cells. Sci Rep. 2021 03 17; 11(1):6104.
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Gao S, Griffin CT. RIPK3 modulates growth factor receptor expression in endothelial cells to support angiogenesis. Angiogenesis. 2021 08; 24(3):519-531.
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Nichols JA, Perego MC, Schütz LF, Hemple AM, Spicer LJ. Hormonal regulation of vascular endothelial growth factor A (VEGFA) gene expression in granulosa and theca cells of cattle1. J Anim Sci. 2019 Jul 02; 97(7):3034-3045.
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Zhang Y, Xiong X, Huai Y, Dey A, Hossen MN, Roy RV, Elechalawar CK, Rao G, Bhattacharya R, Mukherjee P. Gold Nanoparticles Disrupt Tumor Microenvironment - Endothelial Cell Cross Talk To Inhibit Angiogenic Phenotypes in Vitro. Bioconjug Chem. 2019 06 19; 30(6):1724-1733.
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Invernizzi A, Nguyen V, Teo K, Barthelmes D, Fung A, Vincent A, Gillies M. Five-Year Real-World Outcomes of Occult and Classic Choroidal Neovascularization: Data From the Fight Retinal Blindness! Project. Am J Ophthalmol. 2019 08; 204:105-112.