Vascular Endothelial Growth Factor C
"Vascular Endothelial Growth Factor C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A vascular endothelial growth factor that specifically binds to VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2 and VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-3. In addition to being an angiogenic factor it can act on LYMPHATIC VESSELS to stimulate LYMPHANGIOGENESIS. It is similar in structure to VASCULAR ENDOTHELIAL GROWTH FACTOR D in that they both contain N- and C-terminal extensions that were not found in other VEGF family members.
| Descriptor ID |
D042582
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| MeSH Number(s) |
D12.644.276.100.800.400 D12.776.467.100.800.400 D23.529.100.800.400
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Vascular Endothelial Growth Factor C".
Below are MeSH descriptors whose meaning is more specific than "Vascular Endothelial Growth Factor C".
This graph shows the total number of publications written about "Vascular Endothelial Growth Factor C" by people in this website by year, and whether "Vascular Endothelial Growth Factor C" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Vascular Endothelial Growth Factor C" by people in Profiles.
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VEGF-C mediates tumor growth and metastasis through promoting EMT-epithelial breast cancer cell crosstalk. Oncogene. 2021 02; 40(5):964-979.
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Epsin deficiency promotes lymphangiogenesis through regulation of VEGFR3 degradation in diabetes. J Clin Invest. 2018 Aug 31; 128(9):4025-4043.
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The use of human cornea organotypic cultures to study herpes simplex virus type 1 (HSV-1)-induced inflammation. Graefes Arch Clin Exp Ophthalmol. 2015 Oct; 253(10):1721-8.
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CD8+ T cells suppress viral replication in the cornea but contribute to VEGF-C-induced lymphatic vessel genesis. J Immunol. 2012 Jul 01; 189(1):425-32.