Transforming Growth Factor beta1
"Transforming Growth Factor beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.
| Descriptor ID |
D053773
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| MeSH Number(s) |
D12.644.276.374.687.100 D12.644.276.954.775.100 D12.776.467.374.687.100 D12.776.467.942.775.100 D23.529.374.687.100 D23.529.942.775.100
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta1".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta1".
This graph shows the total number of publications written about "Transforming Growth Factor beta1" by people in this website by year, and whether "Transforming Growth Factor beta1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 2 | 0 | 2 |
| 2011 | 2 | 1 | 3 |
| 2013 | 1 | 2 | 3 |
| 2014 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 4 | 0 | 4 |
| 2018 | 2 | 0 | 2 |
| 2019 | 3 | 1 | 4 |
| 2020 | 1 | 2 | 3 |
| 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Transforming Growth Factor beta1" by people in Profiles.
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Effects of transforming growth factor β1 on steroidogenesis of feline granulosa cells cultured in vitro. Reprod Fertil Dev. 2022 Jul; 34(11):789-797.
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Megakaryocyte/platelet-derived TGF-ß1 inhibits megakaryopoiesis in bone marrow by regulating thrombopoietin production in liver. Blood Adv. 2022 06 14; 6(11):3321-3328.
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HIV protease inhibitor ritonavir induces renal fibrosis and dysfunction: role of platelet-derived TGF-ß1 and intervention via antioxidant pathways. AIDS. 2020 06 01; 34(7):989-1000.
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A novel role of LRP5 in tubulointerstitial fibrosis through activating TGF-ß/Smad signaling. Signal Transduct Target Ther. 2020 04 29; 5(1):45.
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Long Noncoding RNA FENDRR Exhibits Antifibrotic Activity in Pulmonary Fibrosis. Am J Respir Cell Mol Biol. 2020 04; 62(4):440-453.
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The Effect of Chitosan Derivatives on the Compaction and Tension Generation of the Fibroblast-populated Collagen Matrix. Molecules. 2019 Jul 26; 24(15).
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Relationship between ETS Transcription Factor ETV1 and TGF-ß-regulated SMAD Proteins in Prostate Cancer. Sci Rep. 2019 06 03; 9(1):8186.
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Oscillatory shear potentiates latent TGF-ß1 activation more than steady shear as demonstrated by a novel force generator. Sci Rep. 2019 04 15; 9(1):6065.
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Inactivation of platelet-derived TGF-ß1 attenuates aortic stenosis progression in a robust murine model. Blood Adv. 2019 03 12; 3(5):777-788.
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PD-1 up-regulation on CD4+ T cells promotes pulmonary fibrosis through STAT3-mediated IL-17A and TGF-ß1 production. Sci Transl Med. 2018 09 26; 10(460).