Transforming Growth Factor beta
"Transforming Growth Factor beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins.
| Descriptor ID |
D016212
|
| MeSH Number(s) |
D12.644.276.374.687 D12.644.276.954.775 D12.776.467.374.687 D12.776.467.942.775 D23.529.374.687 D23.529.942.775
|
| Concept/Terms |
Transforming Growth Factor beta- Transforming Growth Factor beta
- Milk Growth Factor
- Factor, Milk Growth
- Growth Factor, Milk
- TGF-beta
- TGFbeta
- Platelet Transforming Growth Factor
- Bone-Derived Transforming Growth Factor
- Bone Derived Transforming Growth Factor
|
Below are MeSH descriptors whose meaning is more general than "Transforming Growth Factor beta".
Below are MeSH descriptors whose meaning is more specific than "Transforming Growth Factor beta".
This graph shows the total number of publications written about "Transforming Growth Factor beta" by people in this website by year, and whether "Transforming Growth Factor beta" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2002 | 4 | 1 | 5 |
| 2003 | 1 | 0 | 1 |
| 2005 | 3 | 0 | 3 |
| 2006 | 3 | 1 | 4 |
| 2008 | 1 | 2 | 3 |
| 2009 | 3 | 0 | 3 |
| 2010 | 3 | 0 | 3 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 5 | 0 | 5 |
| 2014 | 3 | 2 | 5 |
| 2015 | 7 | 2 | 9 |
| 2016 | 1 | 2 | 3 |
| 2017 | 3 | 0 | 3 |
| 2018 | 0 | 2 | 2 |
| 2021 | 0 | 3 | 3 |
| 2022 | 1 | 2 | 3 |
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Below are the most recent publications written about "Transforming Growth Factor beta" by people in Profiles.
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Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals. Front Immunol. 2022; 13:866181.
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Targeting cancer associated fibroblasts - A TGF-ß based immunotherapy for head and neck squamous cell carcinoma. Oral Oncol. 2022 07; 130:105899.
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Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-ß Signaling Axis in Pancreatic Cancer. Gastroenterology. 2022 06; 162(7):2004-2017.e2.
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Soluble very low-density lipoprotein receptor (sVLDLR) inhibits fibrosis in neovascular age-related macular degeneration. FASEB J. 2021 12; 35(12):e22058.
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Prospective comparison of dysphagia following anterior cervical discectomy and fusion (ACDF) with and without rhBMP-2. Spine J. 2022 02; 22(2):256-264.
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Therapeutic approaches targeting molecular signaling pathways common to diabetes, lung diseases and cancer. Adv Drug Deliv Rev. 2021 11; 178:113918.
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PPARa agonist fenofibrate attenuates iron-induced liver injury in mice by modulating the Sirt3 and ß-catenin signaling. Am J Physiol Gastrointest Liver Physiol. 2021 09 01; 321(4):G262-G269.
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The transcriptional cofactor Jab1/Cops5 is crucial for BMP-mediated mouse chondrocyte differentiation by repressing p53 activity. J Cell Physiol. 2021 08; 236(8):5686-5697.
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Role of the cytoskeleton in the development of a hypofibrotic cardiac fibroblast phenotype in volume overload heart failure. Am J Physiol Heart Circ Physiol. 2019 03 01; 316(3):H596-H608.
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Transcriptomic analysis of differentially expressed genes in the molting gland (Y-organ) of the blackback land crab, Gecarcinus lateralis, during molt-cycle stage transitions. Comp Biochem Physiol Part D Genomics Proteomics. 2018 12; 28:37-53.