"Hepatocyte Growth Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. Its receptor is PROTO-ONCOGENE PROTEINS C-MET.
| Descriptor ID |
D017228
|
| MeSH Number(s) |
D12.644.276.374.420 D12.776.467.374.420 D23.529.374.420
|
| Concept/Terms |
Hepatocyte Growth Factor- Hepatocyte Growth Factor
- Factor, Hepatocyte Growth
- Growth Factor, Hepatocyte
- Scatter Factor
- Factor, Scatter
- Hepatopoietin
- Hepatopoietin A
|
Below are MeSH descriptors whose meaning is more general than "Hepatocyte Growth Factor".
Below are MeSH descriptors whose meaning is more specific than "Hepatocyte Growth Factor".
This graph shows the total number of publications written about "Hepatocyte Growth Factor" by people in this website by year, and whether "Hepatocyte Growth Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
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Below are the most recent publications written about "Hepatocyte Growth Factor" by people in Profiles.
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Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis. Gastroenterology. 2015 Jan; 148(1):181-191.e17.
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The RON receptor tyrosine kinase promotes metastasis by triggering MBD4-dependent DNA methylation reprogramming. Cell Rep. 2014 Jan 16; 6(1):141-54.
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The heparanase/syndecan-1 axis in cancer: mechanisms and therapies. FEBS J. 2013 May; 280(10):2294-306.
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Hepatocyte growth factor and myopia: genetic association analyses in a Caucasian population. Mol Vis. 2009 May 20; 15:1028-35.
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Phosphorylation of MUC1 by Met modulates interaction with p53 and MMP1 expression. J Biol Chem. 2008 Oct 03; 283(40):26985-95.
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Flavonoids promote cell migration in nontumorigenic colon epithelial cells differing in Apc genotype: implications of matrix metalloproteinase activity. Nutr Cancer. 2004; 48(2):182-8.
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Membrane-type matrix metalloproteinases mediate curcumin-induced cell migration in non-tumorigenic colon epithelial cells differing in Apc genotype. Carcinogenesis. 2002 Jun; 23(6):1065-70.
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Hepatocyte growth factor is elevated in chronic lung injury and inhibits surfactant metabolism. Am J Physiol Lung Cell Mol Physiol. 2000 Feb; 278(2):L382-92.