Leukemia Inhibitory Factor
"Leukemia Inhibitory Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An INTERLEUKIN-6 related cytokine that exhibits pleiotrophic effects on many physiological systems that involve cell proliferation, differentiation, and survival. Leukemia inhibitory factor binds to and acts through the lif receptor.
| Descriptor ID |
D053605
|
| MeSH Number(s) |
D12.644.276.374.470 D12.776.467.374.470 D23.529.374.470
|
| Concept/Terms |
Leukemia Inhibitory Factor- Leukemia Inhibitory Factor
- Inhibitory Factor, Leukemia
- Differentiation-Stimulating Factor
- Differentiation Stimulating Factor
- D Factor (Leukemia Inhibitory Factor)
- Myeloid Differentiation-Stimulating Factor
- Differentiation-Stimulating Factor, Myeloid
- Myeloid Differentiation Stimulating Factor
- Cholinergic Differentiation Factor
- Differentiation Factor, Cholinergic
|
Below are MeSH descriptors whose meaning is more general than "Leukemia Inhibitory Factor".
Below are MeSH descriptors whose meaning is more specific than "Leukemia Inhibitory Factor".
This graph shows the total number of publications written about "Leukemia Inhibitory Factor" by people in this website by year, and whether "Leukemia Inhibitory Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukemia Inhibitory Factor" by people in Profiles.
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Retinal Caveolin-1 Modulates Neuroprotective Signaling. Adv Exp Med Biol. 2016; 854:411-8.
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Leukemia inhibitory factor coordinates the down-regulation of the visual cycle in the retina and retinal-pigmented epithelium. J Biol Chem. 2012 Jul 13; 287(29):24092-102.
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gp130 activation in Müller cells is not essential for photoreceptor protection from light damage. Adv Exp Med Biol. 2010; 664:655-61.
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Leukemia inhibitory factor inhibits neuronal development and disrupts synaptic organization in the mouse retina. J Neurosci Res. 2005 Nov 01; 82(3):316-32.
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Nuclear fusion of signaling pathways. Science. 1999 Apr 16; 284(5413):443-4.
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Regulation of bone marrow stromal cell differentiation by cytokines whose receptors share the gp130 protein. J Cell Biochem. 1994 Jan; 54(1):122-33.