"Oxaloacetic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dicarboxylic acid ketone that is an important metabolic intermediate of the CITRIC ACID CYCLE. It can be converted to ASPARTIC ACID by ASPARTATE TRANSAMINASE.
| Descriptor ID |
D062907
|
| MeSH Number(s) |
D02.241.081.337.593.812.750 D02.241.755.648.750
|
| Concept/Terms |
Oxaloacetic Acid- Oxaloacetic Acid
- Acid, Oxaloacetic
- Oxalacetic Acid
- Acid, Oxalacetic
- Ketosuccinic Acid
- 2-Ketosuccinic Acid
- 2 Ketosuccinic Acid
- 2-oxo-Butanedioic Acid
- 2 oxo Butanedioic Acid
|
Below are MeSH descriptors whose meaning is more general than "Oxaloacetic Acid".
Below are MeSH descriptors whose meaning is more specific than "Oxaloacetic Acid".
This graph shows the total number of publications written about "Oxaloacetic Acid" by people in this website by year, and whether "Oxaloacetic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "Oxaloacetic Acid" by people in Profiles.
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Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells. J Proteome Res. 2017 10 06; 16(10):3536-3546.
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GOT1-mediated anaplerotic glutamine metabolism regulates chronic acidosis stress in pancreatic cancer cells. Cancer Lett. 2017 08 01; 400:37-46.
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Salmonella enterica serovar Typhimurium mutants unable to convert malate to pyruvate and oxaloacetate are avirulent and immunogenic in BALB/c mice. Infect Immun. 2009 Apr; 77(4):1397-405.
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Multiple roles of arginine 181 in binding and catalysis in the NAD-malic enzyme from Ascaris suum. Biochemistry. 2007 Dec 18; 46(50):14578-88.
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Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD. Biochemistry. 2002 Oct 08; 41(40):12193-9.
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Lysine 199 is the general acid in the NAD-malic enzyme reaction. Biochemistry. 2000 Oct 03; 39(39):11955-60.