Antimicrobial Cationic Peptides
"Antimicrobial Cationic Peptides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
| Descriptor ID |
D023181
|
| MeSH Number(s) |
D12.644.050 D12.776.543.695.054
|
| Concept/Terms |
Antimicrobial Cationic Peptides- Antimicrobial Cationic Peptides
- Cationic Peptides, Antimicrobial
- Peptides, Antimicrobial Cationic
- Microbicidal Cationic Proteins
- Cationic Proteins, Microbicidal
- Proteins, Microbicidal Cationic
- Cationic Antimicrobial Peptides
- Antimicrobial Peptides, Cationic
- Peptides, Cationic Antimicrobial
|
Below are MeSH descriptors whose meaning is more general than "Antimicrobial Cationic Peptides".
Below are MeSH descriptors whose meaning is more specific than "Antimicrobial Cationic Peptides".
This graph shows the total number of publications written about "Antimicrobial Cationic Peptides" by people in this website by year, and whether "Antimicrobial Cationic Peptides" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 3 | 5 |
| 2015 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antimicrobial Cationic Peptides" by people in Profiles.
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Neutrophil Granule Proteins Inhibit Amyloid Beta Aggregation and Neurotoxicity. Curr Alzheimer Res. 2021; 18(5):414-427.
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Leucinostatins from Ophiocordyceps spp. and Purpureocillium spp. Demonstrate Selective Antiproliferative Effects in Cells Representing the Luminal Androgen Receptor Subtype of Triple Negative Breast Cancer. J Nat Prod. 2020 06 26; 83(6):2010-2024.
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Antimicrobial Peptides Derived from the Immune Defense Protein CAP37 Inhibit TLR4 Activation by S100A9. Invest Ophthalmol Vis Sci. 2020 04 09; 61(4):16.
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Design of Gallinamide A Analogs as Potent Inhibitors of the Cysteine Proteases Human Cathepsin L and Trypanosoma cruzi Cruzain. J Med Chem. 2019 10 24; 62(20):9026-9044.
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Development of a Cell-Based High-Throughput Screening Assay to Identify Porcine Host Defense Peptide-Inducing Compounds. J Immunol Res. 2018; 2018:5492941.
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High Throughput Screening for Natural Host Defense Peptide-Inducing Compounds as Novel Alternatives to Antibiotics. Front Cell Infect Microbiol. 2018; 8:191.
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The antimicrobial protein, CAP37, is upregulated in pyramidal neurons during Alzheimer's disease. Histochem Cell Biol. 2015 Oct; 144(4):293-308.
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A multifunctional peptide based on the neutrophil immune defense molecule, CAP37, has antibacterial and wound-healing properties. J Leukoc Biol. 2015 Feb; 97(2):341-50.
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Corneal wound healing, a newly identified function of CAP37, is mediated by protein kinase C delta (PKCd). Invest Ophthalmol Vis Sci. 2014 Jul 15; 55(8):4886-95.
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Salmonellae PhoPQ regulation of the outer membrane to resist innate immunity. Curr Opin Microbiol. 2014 Feb; 17:106-13.