Stromal Interaction Molecule 1
"Stromal Interaction Molecule 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A stromal interaction molecule that functions in the regulation of calcium influx following depletion of intracellular calcium in the ENDOPLASMIC RETICULUM. It translocates to the plasma membrane upon calcium depletion where it activates the CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL ORAI1.
| Descriptor ID |
D000071737
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| MeSH Number(s) |
D12.776.157.125.806.500 D12.776.543.875.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Stromal Interaction Molecule 1".
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This graph shows the total number of publications written about "Stromal Interaction Molecule 1" by people in this website by year, and whether "Stromal Interaction Molecule 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Stromal Interaction Molecule 1" by people in Profiles.
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STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone. Cell Calcium. 2020 01; 85:102110.
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Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU. Sci Signal. 2015 Mar 03; 8(366):ra23.
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Store-operated calcium entry contributes to abnormal Ca²? signalling in dystrophic mdx mouse myoblasts. Arch Biochem Biophys. 2015 Mar 01; 569:1-9.
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Activating mutations in STIM1 and ORAI1 cause overlapping syndromes of tubular myopathy and congenital miosis. Proc Natl Acad Sci U S A. 2014 Mar 18; 111(11):4197-202.
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Caspase-dependent inhibition of store-operated Ca(2+) entry into apoptosis-committed Jurkat cells. Biochem Biophys Res Commun. 2010 Aug 20; 399(2):198-202.
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Plasma membrane associated membranes (PAM) from Jurkat cells contain STIM1 protein is PAM involved in the capacitative calcium entry? Int J Biochem Cell Biol. 2009 Dec; 41(12):2440-9.