PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2.

Balendran A, Casamayor A, Deak M, Paterson A, Gaffney P, Currie R, Downes CP, Alessi DR. PDK1 acquires PDK2 activity in the presence of a synthetic peptide derived from the carboxyl terminus of PRK2. Curr Biol. 1999 Apr 22; 9(8):393-404.

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subject areas

3-Phosphoinositide-Dependent Protein Kinases
3-Phosphoinositide-Dependent Protein Kinases
Amino Acid Sequence
Amino Acid Sequence
Animals
Animals
Binding Sites
Binding Sites
Cell Line
Cell Line
Enzyme Activation
Enzyme Activation
Glutathione Transferase
Glutathione Transferase
Humans
Humans
Isoenzymes
Isoenzymes
Lipids
Lipids
Molecular Sequence Data
Molecular Sequence Data
Peptides
Peptides
Phosphatidylinositol Phosphates
Phosphatidylinositol Phosphates
Phosphorylation
Phosphorylation
Phosphoserine
Phosphoserine
Phosphothreonine
Phosphothreonine
Protein Binding
Protein Binding
Protein Kinase C
Protein Kinase C
Proto-Oncogene Proteins
Proto-Oncogene Proteins
Proto-Oncogene Proteins c-akt
Proto-Oncogene Proteins c-akt
Rats
Rats
Recombinant Fusion Proteins
Recombinant Fusion Proteins
Saccharomyces cerevisiae
Saccharomyces cerevisiae
Sensitivity and Specificity
Sensitivity and Specificity
Sequence Homology, Amino Acid
Sequence Homology, Amino Acid
Substrate Specificity
Substrate Specificity

authors with profiles

Patrick Gaffney