"Protein Binding" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments.
| Descriptor ID |
D011485
|
| MeSH Number(s) |
G02.111.679 G03.808
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protein Binding".
Below are MeSH descriptors whose meaning is more specific than "Protein Binding".
This graph shows the total number of publications written about "Protein Binding" by people in this website by year, and whether "Protein Binding" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 4 | 4 |
| 1996 | 0 | 12 | 12 |
| 1997 | 0 | 8 | 8 |
| 1998 | 0 | 8 | 8 |
| 1999 | 0 | 12 | 12 |
| 2000 | 0 | 7 | 7 |
| 2001 | 0 | 13 | 13 |
| 2002 | 0 | 14 | 14 |
| 2003 | 0 | 27 | 27 |
| 2004 | 0 | 23 | 23 |
| 2005 | 0 | 18 | 18 |
| 2006 | 0 | 18 | 18 |
| 2007 | 0 | 18 | 18 |
| 2008 | 0 | 23 | 23 |
| 2009 | 0 | 32 | 32 |
| 2010 | 0 | 25 | 25 |
| 2011 | 0 | 24 | 24 |
| 2012 | 0 | 26 | 26 |
| 2013 | 0 | 22 | 22 |
| 2014 | 0 | 26 | 26 |
| 2015 | 0 | 24 | 24 |
| 2016 | 0 | 27 | 27 |
| 2017 | 0 | 19 | 19 |
| 2018 | 0 | 12 | 12 |
| 2019 | 0 | 10 | 10 |
| 2020 | 0 | 15 | 15 |
| 2021 | 0 | 18 | 18 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 3 | 3 |
| 2025 | 0 | 6 | 6 |
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Below are the most recent publications written about "Protein Binding" by people in Profiles.
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Amylin receptor subunit interactions are modulated by agonists and determine signaling. Sci Signal. 2025 Aug 19; 18(900):eadt8127.
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SARS-CoV-2 RNA-binding protein suppresses extracellular miRNA release. RNA Biol. 2025 Dec; 22(1):1-17.
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Cell cycle-dependent TICRR/TRESLIN and MTBP chromatin binding mechanisms and patterns. Genome Biol. 2025 Jul 07; 26(1):194.
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Characterization of the Two-Domain Peptide Binding Mechanism of the Human CGRP Receptor for CGRP and the Ultrahigh Affinity ssCGRP Variant. Biochemistry. 2025 Apr 15; 64(8):1770-1787.
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Structure and unusual binding mechanism of the hyaluronan receptor LYVE-1 mediating leucocyte entry to lymphatics. Nat Commun. 2025 Mar 20; 16(1):2754.
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Mg2+-dependent mechanism of environmental versatility in a multidrug efflux pump. Structure. 2025 Mar 06; 33(3):552-565.e4.
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CACHE Challenge #1: Targeting the WDR Domain of LRRK2, A Parkinson's Disease Associated Protein. J Chem Inf Model. 2024 Nov 25; 64(22):8521-8536.
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Targeting HSP70-E7 Interaction With SHetA2: A Novel Therapeutic Strategy for Cervical Cancer. J Med Virol. 2024 Nov; 96(11):e70088.
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A conserved C-terminal domain of TamB interacts with multiple BamA POTRA domains in Borreliella burgdorferi. PLoS One. 2024; 19(8):e0304839.
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Structure-Activity Relationships of Ligand Binding to Oxysterol-Binding Protein (OSBP) and OSBP-Related Protein 4. J Med Chem. 2023 03 23; 66(6):3866-3875.