"Alkylation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The covalent bonding of an alkyl group to an organic compound. It can occur by a simple addition reaction or by substitution of another functional group.
| Descriptor ID |
D000478
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| MeSH Number(s) |
G02.111.035 G02.607.094 G03.059
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Alkylation".
Below are MeSH descriptors whose meaning is more specific than "Alkylation".
This graph shows the total number of publications written about "Alkylation" by people in this website by year, and whether "Alkylation" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alkylation" by people in Profiles.
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Synthesis of the Dimeric Diarylheptanoids Alpinidinoid C and Officinine B Enabled by Blue-Light-Mediated Triple-Minisci-Type Alkylation. Org Lett. 2024 Oct 25; 26(42):9028-9033.
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Acceptor substrate determines donor specificity of an aromatic prenyltransferase: expanding the biocatalytic potential of NphB. Appl Microbiol Biotechnol. 2020 May; 104(10):4383-4395.
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Determination of Alkyl-Donor Promiscuity of Tyrosine-O-Prenyltransferase SirD from Leptosphaeria maculans. Chembiochem. 2017 12 05; 18(23):2323-2327.
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Simultaneous Upgrading of Furanics and Phenolics through Hydroxyalkylation/Aldol Condensation Reactions. ChemSusChem. 2017 04 10; 10(7):1631-1639.
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Efficient synthesis of N-methoxyindoles via alkylative cycloaddition of nitrosoarenes with alkynes. J Org Chem. 2006 Jan 20; 71(2):823-5.
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The solid-state molecular structure of the S-nitroso derivative of L-cysteine ethyl ester hydrochloride. Nitric Oxide. 2005 Jun; 12(4):261-6.
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1,3- vs 1,5-intramolecular alkylation reactions in isophosphoramide and phosphoramide mustards. Chem Res Toxicol. 2004 Sep; 17(9):1217-26.
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Methods in functional proteomics: two-dimensional polyacrylamide gel electrophoresis with immobilized pH gradients, in-gel digestion and identification of proteins by mass spectrometry. Methods Mol Biol. 2004; 250:263-82.
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[Determination of interacting segments of tRNA(Leu) from cow mammary glands with homologous aminoacyl-tRNA-synthetase by a chemical modification method]. Bioorg Khim. 1990 Dec; 16(12):1647-52.
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Monoclonal antibody-based immunoassay for the determination of cellular enzymatic activity for repair of specific carcinogen-DNA adducts (O6-alkylguanine). Carcinogenesis. 1990 Jan; 11(1):81-7.