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Shanteri Singh

TitleAssistant Professor
InstitutionUniversity of Oklahoma, Norman
DepartmentChemistry/Biochemistry
Addressn/a
620 Parrington Oval
Norman OK 73019
Phone405/325-2088
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    Collapse Research 
    Collapse research activities and funding
    R01GM138800     (SINGH, SHANTERI)Jan 1, 2022 - Dec 31, 2026
    NIH
    A Chemoenzymatic Approach to Accessing Novel Isoprenoid Scaffolds
    Role: Principal Investigator
    R03AI141950     (SINGH, SHANTERI)May 15, 2019 - Apr 30, 2021
    NIH
    The chemoenzymatic synthesis of daptomycin analogs
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Johnson BP, Mandal PS, Brown SM, Thomas LM, Singh S. Ternary complexes of isopentenyl phosphate kinase from Thermococcus paralvinellae reveal molecular determinants of non-natural substrate specificity. Proteins. 2024 Feb 09. PMID: 38333996.
      Citations:    Fields:    
    2. Gardner ED, Johnson BP, Dimas DA, McClurg HE, Severance ZC, Burgett AW, Singh S. Unlocking New Prenylation Modes: Azaindoles as a New Substrate Class for Indole Prenyltransferases. ChemCatChem. 2023 Oct 06; 15(19). PMID: 37954549; PMCID: PMC10634513.
      Citations:    
    3. Johnson BP, Kumar V, Scull EM, Thomas LM, Bourne CR, Singh S. Molecular Basis for the Substrate Promiscuity of Isopentenyl Phosphate Kinase from Candidatus methanomethylophilus alvus. ACS Chem Biol. 2022 01 21; 17(1):85-102. PMID: 34905349.
      Citations:    Fields:    Translation:Cells
    4. Kumar V, Johnson BP, Dimas DA, Singh S. Novel Homologs of Isopentenyl Phosphate Kinase Reveal Class-Wide Substrate Flexibility. ChemCatChem. 2021 Sep 07; 13(17):3781-3788. PMID: 34630731.
      Citations: 2     
    5. Gardner ED, Dimas DA, Finneran MC, Brown SM, Burgett AW, Singh S. Indole C6 Functionalization of Tryprostatin B Using Prenyltransferase CdpNPT. Catalysts. 2020 Nov; 10(11). PMID: 33643664.
      Citations: 3     
    6. Scull EM, Bandari C, Johnson BP, Gardner ED, Tonelli M, You J, Cichewicz RH, Singh S. Chemoenzymatic synthesis of daptomycin analogs active against daptomycin-resistant strains. Appl Microbiol Biotechnol. 2020 Sep; 104(18):7853-7865. PMID: 32725322.
      Citations: 6     Fields:    Translation:Cells
    7. Johnson BP, Scull EM, Dimas DA, Bavineni T, Bandari C, Batchev AL, Gardner ED, Nimmo SL, Singh S. Acceptor substrate determines donor specificity of an aromatic prenyltransferase: expanding the biocatalytic potential of NphB. Appl Microbiol Biotechnol. 2020 May; 104(10):4383-4395. PMID: 32189045.
      Citations: 6     Fields:    Translation:Cells
    8. Bandari C, Scull EM, Bavineni T, Nimmo SL, Gardner ED, Bensen RC, Burgett AW, Singh S. FgaPT2, a biocatalytic tool for alkyl-diversification of indole natural products. Medchemcomm. 2019 Aug 01; 10(8):1465-1475. PMID: 31534661.
      Citations: 9     
    9. Bandari C, Scull EM, Masterson JM, Tran RHQ, Foster SB, Nicholas KM, Singh S. Determination of Alkyl-Donor Promiscuity of Tyrosine-O-Prenyltransferase SirD from Leptosphaeria maculans. Chembiochem. 2017 12 05; 18(23):2323-2327. PMID: 28960770.
      Citations: 12     Fields:    Translation:AnimalsCells
    10. Elshahawi SI, Cao H, Shaaban KA, Ponomareva LV, Subramanian T, Farman ML, Spielmann HP, Phillips GN, Thorson JS, Singh S. Structure and specificity of a permissive bacterial C-prenyltransferase. Nat Chem Biol. 2017 04; 13(4):366-368. PMID: 28166207.
      Citations: 22     Fields:    Translation:Cells
    11. Huber TD, Wang F, Singh S, Johnson BR, Zhang J, Sunkara M, Van Lanen SG, Morris AJ, Phillips GN, Thorson JS. Functional AdoMet Isosteres Resistant to Classical AdoMet Degradation Pathways. ACS Chem Biol. 2016 09 16; 11(9):2484-91. PMID: 27351335.
      Citations: 17     Fields:    Translation:Cells
    12. Peltier-Pain P, Singh S, Thorson JS. Characterization of Early Enzymes Involved in TDP-Aminodideoxypentose Biosynthesis en Route to Indolocarbazole AT2433. Chembiochem. 2015 Oct 12; 16(15):2141-6. PMID: 26289554.
      Citations: 1     Fields:    Translation:Cells
    13. Wang F, Singh S, Xu W, Helmich KE, Miller MD, Cao H, Bingman CA, Thorson JS, Phillips GN. Structural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases. ACS Chem Biol. 2015 Sep 18; 10(9):2048-56. PMID: 26023720.
      Citations: 3     Fields:    Translation:Cells
    14. Elshahawi SI, Ramelot TA, Seetharaman J, Chen J, Singh S, Yang Y, Pederson K, Kharel MK, Xiao R, Lew S, Yennamalli RM, Miller MD, Wang F, Tong L, Montelione GT, Kennedy MA, Bingman CA, Zhu H, Phillips GN, Thorson JS. Structure-guided functional characterization of enediyne self-sacrifice resistance proteins, CalU16 and CalU19. ACS Chem Biol. 2014 Oct 17; 9(10):2347-58. PMID: 25079510.
      Citations: 15     Fields:    Translation:Cells
    15. Singh S, Nandurkar NS, Thorson JS. Characterization of the calicheamicin orsellinate C2-O-methyltransferase CalO6. Chembiochem. 2014 Jul 07; 15(10):1418-21. PMID: 24978950.
      Citations: 3     Fields:    Translation:Cells
    16. Singh S, Peltier-Pain P, Tonelli M, Thorson JS. A general NMR-based strategy for the in situ characterization of sugar-nucleotide-dependent biosynthetic pathways. Org Lett. 2014 Jun 20; 16(12):3220-3. PMID: 24911465.
      Citations: 7     Fields:    Translation:Cells
    17. Wang F, Singh S, Zhang J, Huber TD, Helmich KE, Sunkara M, Hurley KA, Goff RD, Bingman CA, Morris AJ, Thorson JS, Phillips GN. Understanding molecular recognition of promiscuity of thermophilic methionine adenosyltransferase sMAT from Sulfolobus solfataricus. FEBS J. 2014 Sep; 281(18):4224-39. PMID: 24649856.
      Citations: 17     Fields:    Translation:Cells
    18. Zhang J, Singh S, Hughes RR, Zhou M, Sunkara M, Morris AJ, Thorson JS. A simple strategy for glycosyltransferase-catalyzed aminosugar nucleotide synthesis. Chembiochem. 2014 Mar 21; 15(5):647-52. PMID: 24677528.
      Citations: 9     Fields:    Translation:Cells
    19. Singh S, Chang A, Helmich KE, Bingman CA, Wrobel RL, Beebe ET, Makino S, Aceti DJ, Dyer K, Hura GL, Sunkara M, Morris AJ, Phillips GN, Thorson JS. Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. ACS Chem Biol. 2013 Jul 19; 8(7):1632-9. PMID: 23662776.
      Citations: 5     Fields:    Translation:Cells
    20. Gantt RW, Peltier-Pain P, Singh S, Zhou M, Thorson JS. Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis. Proc Natl Acad Sci U S A. 2013 May 07; 110(19):7648-53. PMID: 23610417.
      Citations: 35     Fields:    Translation:Cells
    21. Goff RD, Singh S, Thorson JS. Glycosyloxyamine neoglycosylation: a model study using calicheamicin. ChemMedChem. 2011 May 02; 6(5):774-6. PMID: 21520418.
      Citations: 6     Fields:    Translation:HumansCells
    22. Singh S, Hager MH, Zhang C, Griffith BR, Lee MS, Hallenga K, Markley JL, Thorson JS. Structural insight into the self-sacrifice mechanism of enediyne resistance. ACS Chem Biol. 2006 Aug 22; 1(7):451-60. PMID: 17168523.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    23. Singh S, Cornilescu CC, Tyler RC, Cornilescu G, Tonelli M, Lee MS, Markley JL. Solution structure of a late embryogenesis abundant protein (LEA14) from Arabidopsis thaliana, a cellular stress-related protein. Protein Sci. 2005 Oct; 14(10):2601-9. PMID: 16155204.
      Citations: 44     Fields:    Translation:AnimalsCells
    24. Singh S, Tonelli M, Tyler RC, Bahrami A, Lee MS, Markley JL. Three-dimensional structure of the AAH26994.1 protein from Mus musculus, a putative eukaryotic Urm1. Protein Sci. 2005 Aug; 14(8):2095-102. PMID: 16046629.
      Citations: 11     Fields:    Translation:AnimalsCells
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