"Lipogenesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
De novo fat synthesis in the body. This includes the synthetic processes of FATTY ACIDS and subsequent TRIGLYCERIDES in the LIVER and the ADIPOSE TISSUE. Lipogenesis is regulated by numerous factors, including nutritional, hormonal, and genetic elements.
Descriptor ID |
D050155
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MeSH Number(s) |
G02.111.528 G03.458.249
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lipogenesis".
Below are MeSH descriptors whose meaning is more specific than "Lipogenesis".
This graph shows the total number of publications written about "Lipogenesis" by people in this website by year, and whether "Lipogenesis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2010 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2012 | 0 | 2 | 2 |
2013 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2015 | 1 | 0 | 1 |
2016 | 3 | 0 | 3 |
2017 | 0 | 1 | 1 |
2018 | 0 | 2 | 2 |
2019 | 1 | 1 | 2 |
2020 | 1 | 1 | 2 |
2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Lipogenesis" by people in Profiles.
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Ammonia stimulates SCAP/Insig dissociation and SREBP-1 activation to promote lipogenesis and tumour growth. Nat Metab. 2022 May; 4(5):575-588.
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Leptin decreases de novo lipogenesis in patients with lipodystrophy. JCI Insight. 2020 07 23; 5(14).
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Selective LXR agonist DMHCA corrects retinal and bone marrow dysfunction in type 2 diabetes. JCI Insight. 2020 07 09; 5(13).
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Regular exercise potentiates energetically expensive hepatic de novo lipogenesis during early weight regain. Am J Physiol Regul Integr Comp Physiol. 2019 11 01; 317(5):R684-R695.
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Liver X receptor-a activation enhances cholesterol secretion in lactating mammary epithelium. Am J Physiol Endocrinol Metab. 2019 06 01; 316(6):E1136-E1145.
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Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking. JCI Insight. 2018 07 26; 3(14).
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Lipid metabolism reprogramming and its potential targets in cancer. Cancer Commun (Lond). 2018 May 21; 38(1):27.
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Glucose availability controls adipogenesis in mouse 3T3-L1 adipocytes via up-regulation of nicotinamide metabolism. J Biol Chem. 2017 11 10; 292(45):18556-18564.
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Constitutive expression of microRNA-150 in mammary epithelium suppresses secretory activation and impairs de novo lipogenesis. Development. 2016 11 15; 143(22):4236-4248.
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Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis. Clin Cancer Res. 2016 Nov 01; 22(21):5337-5348.