"Proteasome Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit the function or proteolytic action of the PROTEASOME.
| Descriptor ID |
D061988
|
| MeSH Number(s) |
D27.505.519.389.745.705
|
| Concept/Terms |
Proteasome Inhibitors- Proteasome Inhibitors
- Inhibitors, Proteasome
- Proteasome Inhibitor
- Inhibitor, Proteasome
- Proteasome Endopeptidase Complex Inhibitors
|
Below are MeSH descriptors whose meaning is more general than "Proteasome Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Proteasome Inhibitors".
This graph shows the total number of publications written about "Proteasome Inhibitors" by people in this website by year, and whether "Proteasome Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 1 | 2 |
| 2010 | 2 | 0 | 2 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Proteasome Inhibitors" by people in Profiles.
-
Parallelized gene cluster editing illuminates mechanisms of epoxyketone proteasome inhibitor biosynthesis. Nucleic Acids Res. 2023 02 22; 51(3):1488-1499.
-
Pluronic block copolymers enhance the anti-myeloma activity of proteasome inhibitors. J Control Release. 2019 07 28; 306:149-164.
-
Drug-induced thrombotic microangiopathy: An updated systematic review, 2014-2018. Am J Hematol. 2018 09; 93(9):E241-E243.
-
Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner. PLoS One. 2017; 12(11):e0186924.
-
A Flavin-Dependent Decarboxylase-Dehydrogenase-Monooxygenase Assembles the Warhead of a,ß-Epoxyketone Proteasome Inhibitors. J Am Chem Soc. 2016 Apr 06; 138(13):4342-5.
-
Zinc Protoporphyrin Suppresses ß-Catenin Protein Expression in Human Cancer Cells: The Potential Involvement of Lysosome-Mediated Degradation. PLoS One. 2015; 10(5):e0127413.
-
Endoplasmic reticulum stress and the unfolded protein response: targeting the Achilles heel of multiple myeloma. Mol Cancer Ther. 2013 Jun; 12(6):831-43.
-
Activation of peroxisome proliferator-activated receptor a (PPARa) suppresses hypoxia-inducible factor-1a (HIF-1a) signaling in cancer cells. J Biol Chem. 2012 Oct 12; 287(42):35161-35169.
-
Enhancement of 26S proteasome functionality connects oxidative stress and vascular endothelial inflammatory response in diabetes mellitus. Arterioscler Thromb Vasc Biol. 2012 Sep; 32(9):2131-40.
-
Tyrosine nitration of PA700 links proteasome activation to endothelial dysfunction in mouse models with cardiovascular risk factors. PLoS One. 2012; 7(1):e29649.