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Wei Yue

TitleProf,Asoc
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentPharmaceutical Sciences
AddressCPB 328
1110 N Stonewall Ave
Oklahoma City OK 73117
Phone405/271-6484 ext 47828
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    Collapse Research 
    Collapse research activities and funding
    R01GM146956     (YUE, WEI)Sep 1, 2022 - Jun 30, 2026
    NIH
    Regulation of OATP1B1 and OATP1B3 by lysine acetylation and lysine deacetylase inhibitors
    Role: Principal Investigator
    R01GM094268     (YUE, WEI)Sep 10, 2011 - Aug 31, 2018
    NIH
    Function and regulation of OATP1B1 and OATP1B3
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Farasyn T, Xu C, Yue W. Development of a Rat Sandwich-Cultured Hepatocytes Model Expressing Functional Human Organic Anion Transporting Polypeptide (OATP) 1B3: A Potential Screening Tool for Liver-Targeting Compounds. J Pharm Pharm Sci. 2021; 24:475-483. PMID: 34516949.
      Citations:    Fields:    Translation:AnimalsCells
    2. Kayesh R, Farasyn T, Crowe A, Liu Q, Pahwa S, Alam K, Neuhoff S, Hatley O, Ding K, Yue W. Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interaction Potential of Vemurafenib Using R-Value and Physiologically-Based Pharmacokinetic Models. J Pharm Sci. 2021 01; 110(1):314-324. PMID: 32590030.
      Citations: 3     Fields:    Translation:HumansCells
    3. Crowe AR, Yue W. Semi-quantitative Determination of Protein Expression using Immunohistochemistry Staining and Analysis: An Integrated Protocol. Bio Protoc. 2019 Dec 20; 9(24). PMID: 31867411.
      Citations: 262     
    4. Crowe AR, Miller J, Yue W. Genotyping of the OATP1B1 c. 521 T>C Polymorphism from the Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Specimens: an Optimized Protocol. Bio Protoc. 2019 Aug 20; 9(16). PMID: 31840034.
      Citations:    
    5. Crowe A, Zheng W, Miller J, Pahwa S, Alam K, Fung KM, Rubin E, Yin F, Ding K, Yue W. Characterization of Plasma Membrane Localization and Phosphorylation Status of Organic Anion Transporting Polypeptide (OATP) 1B1 c.521 T>C Nonsynonymous Single-Nucleotide Polymorphism. Pharm Res. 2019 May 15; 36(7):101. PMID: 31093828.
      Citations: 18     Fields:    Translation:HumansCells
    6. Farasyn T, Crowe A, Hatley O, Neuhoff S, Alam K, Kanyo J, Lam TT, Ding K, Yue W. Preincubation With Everolimus and Sirolimus Reduces Organic Anion-Transporting Polypeptide (OATP)1B1- and 1B3-Mediated Transport Independently of mTOR Kinase Inhibition: Implication in Assessing OATP1B1- and OATP1B3-Mediated Drug-Drug Interactions. J Pharm Sci. 2019 10; 108(10):3443-3456. PMID: 31047942.
      Citations: 9     Fields:    Translation:HumansCells
    7. Alam K, Crowe A, Wang X, Zhang P, Ding K, Li L, Yue W. Regulation of Organic Anion Transporting Polypeptides (OATP) 1B1- and OATP1B3-Mediated Transport: An Updated Review in the Context of OATP-Mediated Drug-Drug Interactions. Int J Mol Sci. 2018 Mar 14; 19(3). PMID: 29538325.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    8. Alam K, Farasyn T, Ding K, Yue W. Characterization of Liver- and Cancer-type-Organic Anion Transporting Polypeptide (OATP) 1B3 Messenger RNA Expression in Normal and Cancerous Human Tissues. Drug Metab Lett. 2018; 12(1):24-32. PMID: 29577869.
      Citations: 6     Fields:    Translation:HumansCells
    9. Alam K, Farasyn T, Crowe A, Ding K, Yue W. Treatment with proteasome inhibitor bortezomib decreases organic anion transporting polypeptide (OATP) 1B3-mediated transport in a substrate-dependent manner. PLoS One. 2017; 12(11):e0186924. PMID: 29107984.
      Citations: 16     Fields:    Translation:HumansCells
    10. Pahwa S, Alam K, Crowe A, Farasyn T, Neuhoff S, Hatley O, Ding K, Yue W. Pretreatment With Rifampicin and Tyrosine Kinase Inhibitor Dasatinib Potentiates the Inhibitory Effects Toward OATP1B1- and OATP1B3-Mediated Transport. J Pharm Sci. 2017 08; 106(8):2123-2135. PMID: 28373111.
      Citations: 19     Fields:    Translation:HumansCells
    11. Alam K, Pahwa S, Wang X, Zhang P, Ding K, Abuznait AH, Li L, Yue W. Downregulation of Organic Anion Transporting Polypeptide (OATP) 1B1 Transport Function by Lysosomotropic Drug Chloroquine: Implication in OATP-Mediated Drug-Drug Interactions. Mol Pharm. 2016 Mar 07; 13(3):839-51. PMID: 26750564.
      Citations: 18     Fields:    Translation:HumansCells
    12. Powell J, Farasyn T, Köck K, Meng X, Pahwa S, Brouwer KL, Yue W. Novel mechanism of impaired function of organic anion-transporting polypeptide 1B3 in human hepatocytes: post-translational regulation of OATP1B3 by protein kinase C activation. Drug Metab Dispos. 2014 Nov; 42(11):1964-70. PMID: 25200870.
      Citations: 23     Fields:    Translation:HumansCells
    13. Yue WH, Zou YP, Yu L, Yu CA. Crystallization of mitochondrial ubiquinol-cytochrome c reductase. Biochemistry. 1991 Mar 05; 30(9):2303-6. PMID: 1848094.
      Citations: 7     Fields:    Translation:AnimalsCells
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