Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo.
Ramachandran I, Thavathiru E, Ramalingam S, Natarajan G, Mills WK, Benbrook DM, Zuna R, Lightfoot S, Reis A, Anant S, Queimado L. Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo. Oncogene. 2012 May 31; 31(22):2725-37.
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Adaptor Proteins, Signal Transducing
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Adaptor Proteins, Signal Transducing
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Animals
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Animals
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Apoptosis
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Apoptosis
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Azacitidine
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Azacitidine
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beta Catenin
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beta Catenin
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Blotting, Western
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Blotting, Western
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Cell Cycle
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Cell Cycle
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Cell Line, Tumor
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Cell Line, Tumor
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Cell Proliferation
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Cell Proliferation
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Cervix Uteri
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Cervix Uteri
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DNA Methylation
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DNA Methylation
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Down-Regulation
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Down-Regulation
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Epigenesis, Genetic
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Epigenesis, Genetic
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Female
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Female
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Gene Expression Regulation, Neoplastic
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Gene Expression Regulation, Neoplastic
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Gene Silencing
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Gene Silencing
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Humans
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Humans
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Immunoenzyme Techniques
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Immunoenzyme Techniques
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Mice
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Mice
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Mice, Nude
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Mice, Nude
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Neoplasm Invasiveness
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Neoplasm Invasiveness
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Neovascularization, Pathologic
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Neovascularization, Pathologic
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Promoter Regions, Genetic
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Promoter Regions, Genetic
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Real-Time Polymerase Chain Reaction
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Real-Time Polymerase Chain Reaction
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Repressor Proteins
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Repressor Proteins
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Reverse Transcriptase Polymerase Chain Reaction
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Reverse Transcriptase Polymerase Chain Reaction
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RNA, Messenger
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RNA, Messenger
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Signal Transduction
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Signal Transduction
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Uterine Cervical Neoplasms
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Uterine Cervical Neoplasms
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Wnt Proteins
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Wnt Proteins