"DNA, Circular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Any of the covalently closed DNA molecules found in bacteria, many viruses, mitochondria, plastids, and plasmids. Small, polydisperse circular DNA's have also been observed in a number of eukaryotic organisms and are suggested to have homology with chromosomal DNA and the capacity to be inserted into, and excised from, chromosomal DNA. It is a fragment of DNA formed by a process of looping out and deletion, containing a constant region of the mu heavy chain and the 3'-part of the mu switch region. Circular DNA is a normal product of rearrangement among gene segments encoding the variable regions of immunoglobulin light and heavy chains, as well as the T-cell receptor. (Riger et al., Glossary of Genetics, 5th ed & Segen, Dictionary of Modern Medicine, 1992)
Descriptor ID |
D004270
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MeSH Number(s) |
D13.444.308.283 G02.111.570.820.486.212 G05.360.580.156
|
Concept/Terms |
DNA, Circular- DNA, Circular
- Circular DNAs
- DNAs, Circular
- Circular DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA, Circular".
Below are MeSH descriptors whose meaning is more specific than "DNA, Circular".
This graph shows the total number of publications written about "DNA, Circular" by people in this website by year, and whether "DNA, Circular" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1997 | 1 | 1 | 2 |
2001 | 1 | 0 | 1 |
2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA, Circular" by people in Profiles.
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Double minute amplification of mutant PDGF receptor a in a mouse glioma model. Sci Rep. 2015 Feb 16; 5:8468.
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Mechanism of topology simplification by type II DNA topoisomerases. Proc Natl Acad Sci U S A. 2001 Mar 13; 98(6):3045-9.
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Simplification of DNA topology below equilibrium values by type II topoisomerases. Science. 1997 Aug 01; 277(5326):690-3.
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The effect of ionic conditions on the conformations of supercoiled DNA. II. Equilibrium catenation. J Mol Biol. 1997 Mar 28; 267(2):312-23.
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Somatostatin gene expression in hypothalamus and cortex of aging male rats. Neurobiol Aging. 1990 Jul-Aug; 11(4):409-16.