"DNA, Superhelical" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Circular duplex DNA isolated from viruses, bacteria and mitochondria in supercoiled or supertwisted form. This superhelical DNA is endowed with free energy. During transcription, the magnitude of RNA initiation is proportional to the DNA superhelicity.
| Descriptor ID |
D004278
|
| MeSH Number(s) |
D13.444.308.283.250 G02.111.570.820.486.212.250 G05.360.580.156.250
|
| Concept/Terms |
DNA, Superhelical- DNA, Superhelical
- Superhelical DNA
- DNA, Supertwisted
- Supertwisted DNA
- DNA, Supercoiled
- Supercoiled DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA, Superhelical".
Below are MeSH descriptors whose meaning is more specific than "DNA, Superhelical".
This graph shows the total number of publications written about "DNA, Superhelical" by people in this website by year, and whether "DNA, Superhelical" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 4 | 0 | 4 |
| 1999 | 1 | 1 | 2 |
| 2002 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "DNA, Superhelical" by people in Profiles.
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DNA reshaping by MukB. Right-handed knotting, left-handed supercoiling. J Biol Chem. 2006 Feb 24; 281(8):4606-15.
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The mechanism of type IA topoisomerases. Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19):12126-31.
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13S condensin actively reconfigures DNA by introducing global positive writhe: implications for chromosome condensation. Cell. 1999 Jul 23; 98(2):239-48.
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Mechanisms of separation of the complementary strands of DNA during replication. Genetica. 1999; 106(1-2):131-40.
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Simplification of DNA topology below equilibrium values by type II topoisomerases. Science. 1997 Aug 01; 277(5326):690-3.
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The effect of ionic conditions on DNA helical repeat, effective diameter and free energy of supercoiling. Nucleic Acids Res. 1997 Apr 01; 25(7):1412-8.
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The effect of ionic conditions on the conformations of supercoiled DNA. II. Equilibrium catenation. J Mol Biol. 1997 Mar 28; 267(2):312-23.
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The effect of ionic conditions on the conformations of supercoiled DNA. I. Sedimentation analysis. J Mol Biol. 1997 Mar 28; 267(2):299-311.