Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus.
Labinskyy N, Mukhopadhyay P, Toth J, Szalai G, Veres M, Losonczy G, Pinto JT, Pacher P, Ballabh P, Podlutsky A, Austad SN, Csiszar A, Ungvari Z. Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus. Am J Physiol Heart Circ Physiol. 2009 Apr; 296(4):H946-56.
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Animals
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Animals
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Cells, Cultured
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Cells, Cultured
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Chemokine CCL2
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Chemokine CCL2
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Diabetes Mellitus, Experimental
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Diabetes Mellitus, Experimental
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Disease Models, Animal
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Disease Models, Animal
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Endothelium, Vascular
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Endothelium, Vascular
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Glucose
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Glucose
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Hydrogen Peroxide
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Hydrogen Peroxide
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Inflammation
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Inflammation
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Intercellular Adhesion Molecule-1
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Intercellular Adhesion Molecule-1
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Interleukin-6
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Interleukin-6
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Longevity
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Longevity
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Mice
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Mice
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Mice, Inbred C57BL
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Mice, Inbred C57BL
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Oxidative Stress
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Oxidative Stress
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Oxygen
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Oxygen
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Peromyscus
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Peromyscus
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Reactive Oxygen Species
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Reactive Oxygen Species
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Tumor Necrosis Factor-alpha
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Tumor Necrosis Factor-alpha
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Vascular Resistance
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Vascular Resistance