Chemoprevention of colon and small intestinal tumorigenesis in APC(min/+) mice by SHetA2 (NSC721689) without toxicity.
Benbrook DM, Guruswamy S, Wang Y, Sun Z, Mohammed A, Zhang Y, Li Q, Rao CV. Chemoprevention of colon and small intestinal tumorigenesis in APC(min/+) mice by SHetA2 (NSC721689) without toxicity. Cancer Prev Res (Phila). 2013 Sep; 6(9):908-16.
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Adenomatous Polyposis Coli Protein
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Adenomatous Polyposis Coli Protein
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Administration, Oral
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Administration, Oral
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Animals
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Animals
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Biomarkers
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Biomarkers
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Cell Transformation, Neoplastic
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Cell Transformation, Neoplastic
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Chromans
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Chromans
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Colonic Neoplasms
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Colonic Neoplasms
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Drug-Related Side Effects and Adverse Reactions
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Drug-Related Side Effects and Adverse Reactions
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Female
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Female
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Heart Diseases
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Heart Diseases
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Inflammation
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Inflammation
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Intestinal Neoplasms
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Intestinal Neoplasms
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Intestinal Polyps
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Intestinal Polyps
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Intestine, Small
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Intestine, Small
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Male
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Male
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Mice
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Mice
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Mice, Inbred C57BL
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Mice, Inbred C57BL
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Neovascularization, Pathologic
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Neovascularization, Pathologic
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Thiones
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Thiones