Inositol Polyphosphate 5-Phosphatases
"Inositol Polyphosphate 5-Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Phosphoinositide phosphatases that catalyze the removal of the 5' phosphate from INOSITOL 1,4,5-TRISPHOSPHATE or myo-inositol 1,3,4,5-tetrakisphosphate, resulting in inositol 1,4-bisphosphate and phosphate. They have important functions in the metabolism of INOSITOL PHOSPHATES and inositol 1,4,5-trisphosphate signaling pathways such as CALCIUM SIGNALING.
| Descriptor ID |
D000072181
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| MeSH Number(s) |
D08.811.277.352.650.624.500
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| Concept/Terms |
Inositol Polyphosphate 5-Phosphatases- Inositol Polyphosphate 5-Phosphatases
- Inositol Polyphosphate 5 Phosphatases
- Inositol 5-Phosphatase
- Inositol 5 Phosphatase
- Inositol Triphosphate 5-Phosphatase
- Inositol Triphosphate 5 Phosphatase
- Inositol-Polyphosphate 5-Phosphatase
- Inositol Polyphosphate 5 Phosphatase
- Inositol Polyphosphate 5-Phosphatase
1,4,5-Triphosphate-1,2,4,5-Tetrakisphosphate 5-Phosphatase- 1,4,5-Triphosphate-1,2,4,5-Tetrakisphosphate 5-Phosphatase
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Below are MeSH descriptors whose meaning is more general than "Inositol Polyphosphate 5-Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "Inositol Polyphosphate 5-Phosphatases".
This graph shows the total number of publications written about "Inositol Polyphosphate 5-Phosphatases" by people in this website by year, and whether "Inositol Polyphosphate 5-Phosphatases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
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Below are the most recent publications written about "Inositol Polyphosphate 5-Phosphatases" by people in Profiles.
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TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1. Sci Signal. 2010 May 18; 3(122):ra38.
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IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production. Blood. 2010 Jun 10; 115(23):4699-706.
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IL-6 blocks a discrete early step in lymphopoiesis. Blood. 2005 Aug 01; 106(3):879-85.
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Negative signaling in B lymphocytes induces tyrosine phosphorylation of the 145-kDa inositol polyphosphate 5-phosphatase, SHIP. J Immunol. 1996 Sep 15; 157(6):2234-8.