Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia.
Tang JZ, Carmichael CL, Shi W, Metcalf D, Ng AP, Hyland CD, Jenkins NA, Copeland NG, Howell VM, Zhao ZJ, Smyth GK, Kile BT, Alexander WS. Transposon mutagenesis reveals cooperation of ETS family transcription factors with signaling pathways in erythro-megakaryocytic leukemia. Proc Natl Acad Sci U S A. 2013 Apr 09; 110(15):6091-6.
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Alleles
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Alleles
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Animals
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Animals
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DNA Transposable Elements
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DNA Transposable Elements
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Gene Expression Regulation, Leukemic
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Gene Expression Regulation, Leukemic
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Genotype
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Genotype
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Janus Kinase 2
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Janus Kinase 2
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Leukemia, Erythroblastic, Acute
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Leukemia, Erythroblastic, Acute
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Leukemia, Megakaryoblastic, Acute
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Leukemia, Megakaryoblastic, Acute
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Mice
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Mice
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Mice, Transgenic
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Mice, Transgenic
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Mutagenesis
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Mutagenesis
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Neoplasm Transplantation
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Neoplasm Transplantation
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Oncogene Proteins
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Oncogene Proteins
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Promoter Regions, Genetic
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Promoter Regions, Genetic
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Proto-Oncogene Protein c-ets-1
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Proto-Oncogene Protein c-ets-1
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Proto-Oncogene Proteins c-ets
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Proto-Oncogene Proteins c-ets
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Recombination, Genetic
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Recombination, Genetic
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Sequence Analysis, DNA
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Sequence Analysis, DNA
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Signal Transduction
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Signal Transduction
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Transcription Factors
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Transcription Factors
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Transcriptional Regulator ERG
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Transcriptional Regulator ERG